From the University of Birmingham Institute of Cardiovascular Sciences, Birmingham, United Kingdom (M.P., E.G., P.C., G.Y.H.L.); Department of Internal Medicine and Medical Specialties (M.P., E.G.) and Department of Life, Health and Environmental Sciences (P.C.), University of L’Aquila, Italy; and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Denmark (G.Y.H.L.).