Ep 4: The EXCEL Trial: The Interventionalists’ Perspective
Did you know that left main stem disease is identified in 5% of diagnostic angiography cases? The EXCEL trial was a randomised clinical trial published in 2019 which studied left main stem disease of low or intermediate complexity. The trial came under controversy due to its definition of MI, leading to a loss in patient and public trust, and a deterioration in the relationship between the cardiothoracic and PCI communities.
In this month's featured author episode of the ECR Podcast, interventional fellow Dr George Hunter (Bedfordshire Hospitals NHS Foundation Trust, Bedford, UK) discusses the EXCEL trial from his perspective as a member of the PCI community, based on a recent review paper from the ECR Journal. In this podcast, Dr Hunter discusses the controversy surrounding the trial and the importance of studying left main stem disease in cardiology today.
If you would like to learn more about the EXCEL Trial, view our special collection here.
Prefer to watch in video format? Click here.
Episodes are released on the last Friday of each month.
If you have any questions, please email managingeditor@ecrjournal.com.
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Did you know that coronary vasomotion disorders are a frequent cause of angina in patients with non-obstructed coronary arteries? In this month's episode of the ECR podcast, Dr Andreas Seitz and Dr Peter Ong (Robert-Bosch Hospital, Stuttgart, DE) return to discuss their recent article on the diagnosis of coronary disorders which cause angina (https://www.ecrjournal.com/articles/invasive-diagnosis-coronary-functional-disorders-causing-angina-pectoris) from ECR Journal.
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In the first of a three-part ECR Podcast series on hypertension in women, Dr Isabella Sudano (University Hospital and University of Zurich, Zurich, CH) and Dr Eva Gerdts (Haukeland University Hospital, Bergen, NO) are joined by Prof Juan Tamargo (University Complutense, Madrid, ES) to discuss pharmalogical treatment options and considerations.
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What considerations must be made when screening chronic total occlusion patients undergoing PCI, and how can CT be used in daily practice?
In this month's episode of ECR Podcast, Dr Vinoda Sharma, (Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK) and Dr Abdul Mozid, (Leeds Teaching Hospitals NHS Trust, Leeds, UK) discuss the ways in which CT coronary angiography can be utilised in chronic total occlusion percutaneous coronary interventions, and how the procedures differ across their UK-based practices.
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In this month's episode of ECR Podcast, Dr Vinoda Sharma, (Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK) and Dr Abdul Mozid, (Leeds Teaching Hospitals NHS Trust, Leeds, UK) discuss the ways in which CT coronary angiography can be utilised in chronic total occlusion percutaneous coronary interventions, and how the procedures differ across their UK-based practices.
What are the social factors that impact access to coronary and structural intervention in the current landscape of cardiology? In this month's episode of ECR Podcast, guest editor of ECR's special focus on gender disparities in interventional and structural heart procedures, Dr Natalia Berry (Mid Atlantic Permanente Medical Group, Washington DC, USA) is joined by Dr Renee Bullock-Palmer, (Deborah Heart and Lung Center, Pemberton, NJ, USA) to answer some of these questions.
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What are the clinical challenges in the use of biomarkers to estimate the risk of a cardiovascular event?
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Join Prof Juan Carlos Kaski (St George’s University of London, UK) and Dr Aernoud Fiolet (University Medical Center Utrecht, Netherlands) as they explore topics such as how guidelines currently view anti-inflammatory approaches and main molecules under investigation.
Supported by an unrestricted educational grant from NOVO NORDISK A/S.
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Supported by an unrestricted educational grant from NOVO NORDISK A/S.
Inflammation and Atherosclerosis – What is the Link with CKD? Join Prof Juan Carlos Kaski (St George’s University of London, UK) and Prof Lina Badimon (Hospital of Santa Creu and San Pau, Barcelona, Spain) as they discuss that very question.
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Prof Juan Carlos Kaski (St George’s University of London, UK) alongside Dr Peter Libby (Brigham and Women’s Hospital, Boston, US) provide us with a short and concise discussion regarding Therapeutic Targets and Mode of Action.
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Inflammatory Signalling in Atherosclerosis and CKD is the topic of interest in this short peer to peer discussion involving Prof Juan Carlos Kaski (St George’s University of London, UK) and Prof Paul Ridker (Brigham and Women’s Hospital, Boston, US).
Supported by an unrestricted educational grant from NOVO NORDISK A/S.
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Supported by an unrestricted educational grant from NOVO NORDISK A/S.
Prof Juan Carlos Kaski (St George’s University of London, UK) is joined by Prof Paul Ridker (Brigham and Women’s Hospital, Boston, US) to discuss Unmet Clinical Needs in Atherosclerosis and Chronic Kidney Disease where they cover topics such as elevated hsCRP and chronic kidney disease.
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Prof Jean-Claude Tardif (Montreal Heart Institute, Canada) gives us a comprehensive overview of the COLCOT trial.
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Did you know that atrial arrhythmias are the most common complication in adults with congenital heart disease?
Dr Irene Martin de Miguel (Hospital General Universitario Gregorio Marañón, Madrid, Spain) joins us in this featured author episode to outline her recent review article, Atrial Fibrillation in Congenital Heart Disease. In this podcast, Dr de Miguel provides an overview of the current knowledge of AF in CHD, giving practical recommendations for your everyday practice.
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Dr Irene Martin de Miguel (Hospital General Universitario Gregorio Marañón, Madrid, Spain) joins us in this featured author episode to outline her recent review article, Atrial Fibrillation in Congenital Heart Disease. In this podcast, Dr de Miguel provides an overview of the current knowledge of AF in CHD, giving practical recommendations for your everyday practice.
Is there enough evidence to support the prognostic value of coronary physiology measurements in pre-and post-PCI settings? Is post-PCI FFR ready for clinical practice?
Today's episode features co-hosts Dr Peter Ong and Dr Andreas Seitz (Robert-Bosch Hospital, Stuttgart, DE) who together summarise the main results from the TARGET FFR and DEFINE-FLOW trials that were presented at TCT Connect 2020 and published recently in ECR journal, in the context of the existing literature.
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Today's episode features co-hosts Dr Peter Ong and Dr Andreas Seitz (Robert-Bosch Hospital, Stuttgart, DE) who together summarise the main results from the TARGET FFR and DEFINE-FLOW trials that were presented at TCT Connect 2020 and published recently in ECR journal, in the context of the existing literature.
Did you know that CV disease is the leading cause of death in women and that women are more likely to die of heart disease compared to men? Dr Erin Michos (John Hopkins Uni, US) and Dr Martha Gulati (Uni of Arizona, US) join us on the inaugural episode of the ECR podcast series to discuss issues surrounding women in heart disease. Together they explore a variety of topics that are addressed in the latest special focus issue in the European cardiology Review journal.
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