AF Stroke Prevention – Applying New Guidance in the Real World

Published: 04 September 2024

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Overview

First presented at ESC 2024, this on-demand programme sees Prof Gregory Lip (University of Liverpool, UK) lead a faculty comprising Prof Elena Arbelo (University of Barcelona, ES), Prof Thorsten Hanke (Asklepios Klinikum Harburg, DE) and Prof Richard Whitlock (McMaster University, CA) review the application of the latest AF guidance in a clinical setting.

 

This case-based programme explores the considerations of risks in the assessment of treatment strategies, the impact of the guidelines on decision-making and the evidence supporting non-pharmacological stroke prevention.

 

Learning Objectives:

  • Recall the risk of ischaemic stroke in AF patients
  • Compare therapeutic efficacy and risk between left atrial appendage closure and oral anticoagulation in atrial fibrillation
  • Review European guideline updates on the use of left atrial appendage closure in atrial fibrillation
  • Summarise the clinical evidence behind non-pharmacological approaches to stroke prevention in atrial fibrillation

 

The live ESC 2024 symposium was CME-accredited, this on-demand version is not.

 

This programme is supported by an unrestricted educational grant from AtriCure Inc.

More from this programme

Part 1

Introduction and Patient Case

Prof Lip provides a brief introduction to the session, before Prof Arbelo presents the case of a patient with severe mitral regurgitation due to mitral valve prolapse, with persistent atrial fibrillation and severe LA enlargement.

Part 2

Faculty Discussion on Balancing Risk

Prof Lip leads the discussion on balancing risk, with considerations including a surgical approach over transcatheter edge-to-edge repair and the risk of stroke in AF post-surgery.

Part 3

AF Guideline Updates

Prof Hanke reviews the evolution of the AF guidelines and considers the implications for cardiologists, including the requirement to insist on concomitant AF ablation and peri-procedural left atrial appendage (LAA) closure, to not forget stand alone EP surgery for patients with persistent AF and to not stop oral anticoagulants after surgical LAA closure.

Part 4

Evidence for Non-pharmacological Stroke Prevention

Prof Whitlock considers non-pharmacological stroke prevention, specifically left atrial appendage occlusion during cardiac surgery. He reviews the LAAOS III study, in addition to the multi-centre ATLAAC trial, that commenced early 2024.

Part 5

Patient Case Revisited, Faculty Discussion and Close

Prof Arbelo revisits the patient case in context of the 2024 ESC guideline recommendations for surgical left atrial appendage occlusion. Prof Lip leads a faculty discussion and moderates audience questions.

Faculty Biographies

Gregory YH  Lip

Gregory YH Lip

Professor of Cardiovascular Medicine

Prof Lip is Price-Evans Chair of Cardiovascular Medicine at the University of Liverpool, UK. He is also director of the Liverpool Centre for Cardiovascular Science at the University of Liverpool and Liverpool Heart & Chest Hospital. He is also Distinguished Professor at Aalborg University, Denmark; and Adjunct Professor, Yonsei University, Seoul, Korea. He is also Visiting Professor at the University of Aston in Birmingham, England; Adjunct Professor of Cardiovascular Sciences, Aalborg University, Denmark; and Visiting Professor of Cardiology, Belgrade University, Serbia.

Prof Lip is a member of the European Heart Rhythm Association and is Chairman of its scientific documents committee. He  serves on the board of the Working Group on Thrombosis of the European Society of Cardiology. He was clinical adviser for the National Institute for Health and Care Excellence guidelines on AF management.

Professor Gregory Lip is a section editor for AER.

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Elena Arbelo

Elena Arbelo

Associate Professor

Prof Elena Arbelo is a Cardiac Electrophysiologist at Hospital Clínic of Barcelona, Barcelona, Spain, where she serves as Coordinator of the Cardiac Genetic Diseases and Sudden Arrhythmic Death Unit.

She is a Clinical Professor at the University of Barcelona and a researcher at the Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). Prof Arbelo is a member of several committees of the European Society of Cardiology (ESC), the European Heart Rhythm Association (EHRA), and the Heart Rhythm Society (HRS).

Prof Arbelo is a committee member for several large-scale European Registries to gather data on atrial fibrillation and guideline implementation. She serves as a member of the Working Group on Atrial Fibrillation of the International Consortium for Health Outcomes Measurement (ICHOM). 

Prof Arbelo is an editorial board member of Arrhythmia & Electrophysiology Review journal. 

 

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