ESC 24: Hot Line & Late-breaking Science Video Collection

Published: 15 August 2024

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Overview

What's hot at the ESC Congress 2024?

Stay ahead of the curve with our faculty-led coverage of the European Society of Cardiology Congress in London. From groundbreaking trials to expert insights, we've got you covered.

  • Watch our View From the Thoraxcenter series for practice-focused reviews of the most anticipated trials from interventional experts, Prof Nicolas Van Mieghem and Dr Joost Daemen
  • For a deeper dive into key hot line clinical trial data and its applicability, host, Dr Harriette Van Spall meets with principal investigators in her Late-Breaker Discussion series.
  • View a condensed summary of the crucial takeaways from each day in our Wrap-Up series led by Dr Mirvat Alasnag.
  • Our short, bite-sized Expert Interviews with select faculty will focus on data, take-home messages for practice and the future of their field.

Get ready for a deep dive into the latest cardiology research. Our coverage of the ESC Congress is coming soon.

More from this programme

Part 1

View From the Thoraxcenter: What's Hot at ESC 24?

About the episode

ESC Congress 2024 — FINEARTS-HF shows finerenone reduces cardiovascular death and total of worsening heart failure (HF) events over median follow-up of 32 months.

Host, Dr Harriette Van Spall (McMaster University, CA) is joined by Principal investigator, Dr Scott Solomon (Brigham And Women's Hospital & Harvard Medical School, US) to discuss findings from the landmark FINEARTS-HF trial (NCT04435626; Bayer).

A multicenter, randomized, double-blind, placebo-controlled trial assessed the efficacy and safety of finerenone in 6016 patients with heart failure (NYHA class II-IV) and preserved left ventricular ejection fraction (LVEF ≥ 40%). The study, conducted across 660 sites in the United States, evaluated the impact of finerenone on the composite endpoint of cardiovascular death and heart failure events over a 42-month follow-up period.

Finerenone significantly reduced the risk of cardiovascular death, total heart failure events, and improved overall health status in patients with heart failure and mildly reduced or preserved ejection fraction. These benefits were observed across various subgroups, including those with different LVEF and those taking SGLT2 inhibitors. While hyperkalemia was more common, hypokalemia was less common in patients receiving finerenone.

Recorded remotely from Boston and Hamilton, 2024.

Editors: Jordan Rance and Mirjam Boros.
Videographers: Mike Knight, Dan Brent, Oliver Miles, Tom Green, David-Ben-Harosh.

Support: This is an independent interview produced by Radcliffe Cardiology. 

Faculty Biographies

Harriette Van Spall

Harriette Van Spall

Associate Professor of Medicine, Director of E-Health and Virtual Care

Dr Harriette Van Spall is an Associate Professor of Medicine and cardiologist and serves as Director of E-Health at McMaster University, Canada. She completed her medical and postgraduate clinical training at the University of Toronto and earned a Master of Public Health degree at Harvard University, US. Dr Van Spall is a Canadian Institutes of Health Research-funded clinical trialist and researcher with a focus on heart failure, health services, and health disparities.

She has garnered more than $4 million in research funding, has won several research awards, and has published her work in high-impact medical journals. She is an invited speaker, media correspondent, and editorial board member active in peer review at several high-impact medications journals and grant funding agencies, including Canadian Institutes of Health Research and Heart and Stroke Foundation of Canada.

Dr Van Spall is an Editorial Board…

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Scott Solomon

Scott Solomon

Director, Noninvasive Cardiology / Professor

Prof Scott D Solomon is the Edward D Frohlich Distinguished Chair at Harvard Medical School, Director of Noninvasive Cardiology and Senior Physician at Brigham and Women’s Hospital. His research group has played a leading role in clinical trials in heart failure, hypertension and myocardial infarction. 

He received his AB from Williams College and his MD from Harvard Medical School. 

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