ESC 24: Hot Line & Late-breaking Science Video Collection

Published: 15 August 2024

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Overview

What's hot at the ESC Congress 2024?

Stay ahead of the curve with our faculty-led coverage of the European Society of Cardiology Congress in London. From groundbreaking trials to expert insights, we've got you covered.

  • Watch our View From the Thoraxcenter series for practice-focused reviews of the most anticipated trials from interventional experts, Prof Nicolas Van Mieghem and Dr Joost Daemen
  • For a deeper dive into key hot line clinical trial data and its applicability, host, Dr Harriette Van Spall meets with principal investigators in her Late-Breaker Discussion series.
  • View a condensed summary of the crucial takeaways from each day in our Wrap-Up series led by Dr Mirvat Alasnag.
  • Our short, bite-sized Expert Interviews with select faculty will focus on data, take-home messages for practice and the future of their field.

Get ready for a deep dive into the latest cardiology research. Our coverage of the ESC Congress is coming soon.

More from this programme

Part 1

View From the Thoraxcenter: What's Hot at ESC 24?

About the episode

ESC Congress 2024 — No benefit of continuing oral anticoagulation during TAVI procedure. 

Investigator, Dr Dirk-Jan van Ginkel (St Antonius Hospital, NL) joins us to discuss the result of the POPular PAUSE TAVI trial (NCT04437303; St Antonius Hospital). Presented for the first time at ESC 2024, this multicenter, randomized, open-label clinical trial compared the safety and efficacy of continuous versus interrupted oral anticoagulant (OAC) therapy during transcatheter aortic valve implantation (TAVI). A total of 858 patients were randomized to either continued or interrupted OAC treatment. The primary outcome was a composite of cardiovascular death, any stroke, myocardial infarction, major vascular complications, and VARC-3 defined type 2-4 bleeding events at 30 days post-TAVI.

Findings show that in patients undergoing TAVI with an indication for oral anticoagulation, periprocedural continuation was not found to be noninferior to interruption of oral anticoagulation during TAVI.

Interview Questions:

  1. What is the background to the POPular PAUSE TAVI trial?
  2. What was the study design, eligibility criteria and outcome measures?
  3. What are the findings?
  4. Are there any patient subgroups that benefit more from continuous OAC?
  5. What are the take-home messages for practice? (+Should these findings influence guidelines?)
  6. What are the next steps?

Recorded on-site at ESC Congress 2024, London.  

Editors: Jordan Rance and Mirjam Boros. 
Videographers: Mike Knight, Dan Brent, Oliver Miles, Tom Green, David-Ben-Harosh.  

Support: This is an independent interview produced by Radcliffe Cardiology.

Faculty Biographies

Dirk-Jan van Ginkel

View full profile

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