The Hybrid Approach in CAD with Restore® DEB: Use and Clinical Outcomes in the HYPER Study

Published: 18 June 2024

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Overview

In this comprehensive video series, Dr Alfonso Ielasi (IRCCS Ospedale Galeazzi Sant'Ambrogio, IT) delves into the approach of using Restore® Drug-Eluting Balloon (DEB) in treating Coronary Artery Disease (CAD). 

This video series is supported by

Learning Objectives

  • Gain insights into the findings of the HYPER Study presented by Dr Ielasi, focusing on the hybrid approach combining a drug-eluting stent and the Restore® drug-coated balloon (DEB)
  • Understand the technological features and benefits of the Restore® DEB as explained by Dr Ielasi during the video interview
  • Comprehend the study design, including participant selection criteria and clinical outcomes of the HYPER Study
  • Recognise the significance of procedural success rates DoCE rates in evaluating the effectiveness and safety of the hybrid approach
  • Appreciate the long-term stability of favourable outcomes, including low DoCE rates, observed up to the 3-year follow-up period in the HYPER Study
  • Interpret the implications of the HYPER Study findings for clinical practice, particularly in the context of coronary artery disease management and treatment strategies involving drug-eluting stents and drug-coated balloons

Target Audience

  • Interventional Cardiologists

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About the episode

This video features Dr Alfonso Ielasi (IRCCS Ospedale Galeazzi Sant'Ambrogio, Milano, IT) presenting a dynamic poster focused on the 2-Year Follow-up of a Hybrid Strategy for Diffuse Coronary Artery Disease (CAD). He highlights the challenging nature of de novo diffuse coronary artery disease (CAD) in interventional cardiology, where limited treatment options exist beyond stent implantation. To address this, the study explores a hybrid approach combining last generation Drug-Eluting Stent (DES) and Restore® Drug-Coated Balloon (DCB) to limit the total stent length.

 

The one-year clinical events demonstrated promising results, particularly with a Device-Oriented Composite End-point. This video presents the 2-year clinical outcomes, offering further insights into the effectiveness of this hybrid strategy for diffuse CAD treatment.

Faculty Biographies

Alfonso Ielasi

Alfonso Ielasi

Interventional Cardiologist

Dr Alfonso Ielasi is an Interventional Cardiologist at IRCCS Ospedale Galeazzi Sant'Ambrogio, Milano, IT.

Dr Ielasi's interests include interventional cardiovascular therapies of acute coronary syndromes, unprotected left main disease, complex coronary artery disease and aortic valve stenosis.

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