TCT 2024 Late-Breaking Science Collection

Published: 17 October 2024

  • Views:

    Views Icon 2697

  • Likes:

    Heart Icon 7
Average (ratings)
No ratings
Your rating

Overview

Keep informed with our video collection unveiling data from the Transcatheter Cardiovascular Therapeutics Conference in Washington. With expert insights on late-breaking trials and critical findings, you won't want to miss our #TCT24 coverage.

  • For practice-focused reviews of the most anticipated trials, watch our recurring View From the Thoraxcenter series, hosted by Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcenter, Erasmus MC, Rotterdam, NL).
  • Our short Expert Interviews with select faculty offer focused data analysis and take-home messages for practice.
  • To delve deeper into insights on the most pertinent trials, catch our Highlights.

Dive into the latest cardiology research with our upcoming TCT Conference coverage.

More from this programme

Part 1

View From the Thoraxcenter: What's Hot at TCT 24?

1 session
View from the Thoraxcenter: TCT 24 Late-breaking Preview Watch now

Part 2

Expert Interviews

9 sessions
SIRONA: Sirolimus- vs. Paclitaxel-Coated Balloon Angioplasty in the Femoropopliteal Artery Watch now
TAVR UNLOAD: Transcatheter Aortic Valve Replacement in Patients with Heart Failure and Moderate Aortic Stenosis Watch now
EVOLVED: Early Intervention in Patients with Asymptomatic Severe Aortic Stenosis and Left Ventricular Decompensation Watch now
MATTERHORN: Transcatheter Repair Versus Surgery in Mitral Regurgitation Watch now
INFINITY-SWEDEHEART: DynamX Bioadaptor in Patients with Complex Lesions Watch now
Pooled Analysis of the RHEIA and PARTNER 3 Trials: Transcatheter vs. Surgical Aortic Valve Replacement in Women Watch now
CLASP IID: Two-Year Outcomes of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation Watch now
ECLIPSE: Orbital Atherectomy vs. Conventional Balloon Angioplasty in Calcified Coronary Arteries Prior to DES Implantation Watch now
TRISCEND II: Transcatheter Valve Replacement vs. Optimal Medical Therapy for Severe Tricuspid Regurgitation Watch now

Part 3

Highlights

2 sessions
5 Trials That Will Change My Practice with Dr Mirvat Alasnag Watch now
2 Trials That Will Change My Practice with Dr Sahil Parikh Watch now

About the episode

TCT Conference 2024 - Clinical outcomes between percutaneous mitral valve repair (PMVR) and mitral valve surgery in patients with atrial mitral regurgitation (MR).

Dr Stephan Baldus (University of Köln Medical Center, DE) joins us onsite at TCT Conference to discuss the findings from MATTERHORN (NCT02371512; University of Köln).

MATTERHORN is a multicenter, randomized controlled clinical trial, where high-surgical risk patients with advanced functional or ischemic mitral regurgitation and reduced left ventricular ejection fraction (LVEF ≥ 20%) were randomized to receive either the MitraClip system, or mitral valve surgical repair. 210 patients were enrolled in the study and were followed-up 12 months post intervention. The primary outcome measures were composite of death, rehospitalisation for heart failure, reintervention, assist device implantation and stroke within 12 months of surgery.

Findings showed that no subgroup-specific differences were found in the recurrence of MR between subgroups treated with the MitraClip system and subgroups who underwent mitral valve surgery; however, the MitraClip system demonstrated better safety outcomes than mitral valve surgery. Non-elevated event rates were found for the primary endpoints in all sub-groups for the MitrClip system and surgery.

Interview Questions:

  1. What is the reasoning behind this trial? 
  2. What are the current unmet needs in mitral regurgitation management?
  3. Could you tell us about the patient population and study design for MATTERHORN?
  4. What were the key findings?
  5. Were there any surprising or unexpected results?
  6. What further study is needed in this area?

Recorded at TCT Conference in Washington, 2024.

Editors: Yazmin Sadik, Jordan Rance
Video Specialist: David Ben-Harosh, Oliver Miles

Support: This is an independent interview produced by Radcliffe Cardiology.

Faculty Biographies

Stephan Baldus

Stephan Baldus

Professor and Chair

Professor Baldus is a distinguished cardiologist specialising in internal medicine and intensive care. With over 27 years of experience, he currently works at the Department of Cardiology at the University Hospital Cologne.

Dr. Baldus studied medicine at the University of Ulm and the University of Hamburg. He has conducted significant research, receiving grants from notable organisations like the Max Planck Society and the German Foundation for Heart Research.

His contributions to medicine have earned him several accolades, including the Teacher of the Year Award from the University of Hamburg in 2005 and the Albert Fraenkel Award from the German Society of Cardiology in 2008. Professor Baldus has been active on various committees, including those for the German Cardiac Society and the European Society of Cardiology.

An accomplished researcher, he has published hundreds of scientific papers, focusing on topics such as pulmonary…

View full profile

Comments

You must be to comment. If you are not registered, you can register here.