EP 97: Conversations about Hypertrophic Cardiomyopathy: Differential Diagnosis, Genetic Testing & Patient-centric Therapy with Dr Owens
In the finale of our series "Conversations about Hypertrophic Cardiomyopathy", Dr Ankur Kalra welcomes, Dr Anjali Tiku Owens, for a dynamic and practical discussion.
Dr Owens is Medical Director of the Center for Inherited Cardiac Disease and Associate Professor of Medicine at the Hospital of the University of Pennsylvania.
This series is supported by an unrestricted educational grant from Bristol Myers Squibb. Please see www.camzyosrems.com for important safety information.
In this week’s episode, Dr Kalra and Dr Owens take us on a journey through the complexities of hypertrophic cardiomyopathy (HCM), with focus on the diagnostic challenges and breakthroughs in this field.
Emphasising with the critical importance of making accurate diagnoses, Dr Owens shares her insights into identifying the common mimickers of HCM through a structured approach starting with taking the patients history.
As the conversation delves deeper, Dr Owens discusses the various diagnostic tools and tests used to rule out other conditions and uncover the underlying aetiology. She navigates us through the algorithm for interpreting genetic test results, differentiating pathogenic variants, benign variants and variants of uncertain significance (VUS). Dr Owens talks about the wider implications for family members and the cases in which she recommends screening.
Dr Kalra asks Dr Owens about her approach to exercise in HCM patients. Additionally, they cover the debated topic of defibrillator therapy and the use of HCM Risk-SCD risk calculator.
Dr Owens provides an overview of the treatment paradigms for HCM, touching on haemodynamic classifications, symptomatology and the evaluation of sudden death risk.
What are the most common mimickers of HCM? What is Dr Owens and her heart team approach to decision making? What is the role of genetic testing in patients with HCM?
This content is intended for US-based physicians.
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This series is supported by an unrestricted educational grant from Bristol Myers Squibb.
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In this week's Parallax, Dr Ankur Kalra welcomes back Dr Jag Singh to discuss Dr Singh's recently published book, "Future Care," which delves into the exciting evolution of medicine over the next 5 to 10 years.
As we adapt to the changes brought about by the pandemic, Dr Singh outlines the necessary steps to foster a reality in which we can utilize these technologies to create more time for human connection.
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As we adapt to the changes brought about by the pandemic, Dr Singh outlines the necessary steps to foster a reality in which we can utilize these technologies to create more time for human connection.
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What are the key pillars of self-care and what do dirty windshields have to do with it? How can you take meditation “off the matt”? What has chronobiology and Ayurveda taught us about working with, rather than against, our circadian rhythm?
In the final episode of our burnout and resilience series, Kavitha and Ankur give you some practical tools of self-care to help you avoid burnout. Kavitah Chinnaiyan, MD, is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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In the final episode of our burnout and resilience series, Kavitha and Ankur give you some practical tools of self-care to help you avoid burnout. Kavitah Chinnaiyan, MD, is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
What does mindfulness have to do with burnout? Is our definition of success driving our stress and anxiety? How can we channel our ego into something positive?
In our second episode on burnout and resilience, Kavitah Chinnaiyan, MD, and Ankur take a deeper dive into mindfulness and training the brain to move from Default-Mode to Task-Positive Networks. Kavitah is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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In our second episode on burnout and resilience, Kavitah Chinnaiyan, MD, and Ankur take a deeper dive into mindfulness and training the brain to move from Default-Mode to Task-Positive Networks. Kavitah is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
How do you nurture resilience in the midst of competition, envy and individualism? What is moral injury? Is the current healthcare landscape driving physicians to burnout? Are we too focused on data and study results? These are some of the questions discussed by Kavitah Chinnaiyan, MD, award winning author and Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI, and host Ankur, in the first episode of this three-part series on burnout and resilience. Send us your thoughts to this episode for Ankur to share in future episodes: pocast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Madhav Swaminathan joins Ankur Kalra for a dynamic conversation about diversity, inclusion and leadership. Madhav shares how, as President of large organisation like the American Society of Echocardiography, he works to create an inclusive platform with opportunities for individuals from diverse backgrounds.
Ankur and Madhav also discuss positive traits of leadership, why we should embrace failure and the importance of mentorship throughout all stages of one’s medical career. Send us your comments to this episode for Ankur to share in future episodes: pocast@radciffe-group.com. Guest @mswami001.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Ankur and Madhav also discuss positive traits of leadership, why we should embrace failure and the importance of mentorship throughout all stages of one’s medical career. Send us your comments to this episode for Ankur to share in future episodes: pocast@radciffe-group.com. Guest @mswami001.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Following the recent controversy surrounding physician portraits displayed in medical hallways, Ankur spoke to Harriette GC Van Spall MD to unpick this hot topic brought back to life by a recent article penned by Jeffrey Flier (former Dean of Harvard Medical School) in The Boston Globe.
Harriette is an Associate Professor of Medicine at the Department of Medicine, Cardiology and the Department of Health Research Methods, Evidence and Impact at McMaster University and the Population Health Research Institute in Hamilton, ON, Canada. In this episode, Ankur and Harriette discuss why this issue is so contentious, what the current state of medical walls represents, why this may be an issue and what alternative medical walls could look like. Harriette also shares her thoughts on how this topic relates to the maintenance of hierarchical power structures in academic institutions, calling for more collaborative leadership and management styles. Guest @hvanspall.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Harriette is an Associate Professor of Medicine at the Department of Medicine, Cardiology and the Department of Health Research Methods, Evidence and Impact at McMaster University and the Population Health Research Institute in Hamilton, ON, Canada. In this episode, Ankur and Harriette discuss why this issue is so contentious, what the current state of medical walls represents, why this may be an issue and what alternative medical walls could look like. Harriette also shares her thoughts on how this topic relates to the maintenance of hierarchical power structures in academic institutions, calling for more collaborative leadership and management styles. Guest @hvanspall.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
In celebration of this month’s ‘National Eat Your Vegetables Day’, this week’s guest is @TheVeggieMD, one of the most prominent physicians on social media! Dr Danielle Belardo MD is a Cardiology Fellow, American Board of Internal Medicine certified and a member of the American College of Cardiology Nutrition and Lifestyle Sub-Committee.
In this episode, Ankur and Danielle speak about the evidence in favour of a whole-food plant-based diet to improve cardiovascular health, the ACC prevention guidelines, how to talk to patients about positive dietary change, the issue of lack of nutrition training in cardiovascular fellowships and what Danielle’s diet looks like as a busy whole-food plant-based cardiology fellow. On her own podcast ‘Nutrition Rounds’ Danielle has discussions about evidence-based plant-based nutrition with physicians who are leading experts in nutrition and health.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
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In this episode, Ankur and Danielle speak about the evidence in favour of a whole-food plant-based diet to improve cardiovascular health, the ACC prevention guidelines, how to talk to patients about positive dietary change, the issue of lack of nutrition training in cardiovascular fellowships and what Danielle’s diet looks like as a busy whole-food plant-based cardiology fellow. On her own podcast ‘Nutrition Rounds’ Danielle has discussions about evidence-based plant-based nutrition with physicians who are leading experts in nutrition and health.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Listen to our first episode with two guests! Ankur spoke with Emmanouil S Brilakis, MD and Michael Megaly, MD from the Minneapolis Heart Institute, Abbott Northwestern Hospital about their article on the role of drug-coated balloons in small-vessel coronary artery disease (SVD) published in US Cardiology Review 13.1. Percutaneous coronary intervention of SVD remains challenging due to difficulties with device delivery and high restenosis rate, making drug-coated balloons an attractive emerging option in patients with SVD.
In this brilliant conversation, Ankur, Emmanouil and Michael unravel the potential advantages, challenges and practical realities of using drug-coated balloons in SVD, and the findings of the latest randomised controlled trials studying this area.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology. [Disclaimer: The use of drug-coated balloons in coronay intervention is still off-label; it has not been approved by the FDA.]
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In this brilliant conversation, Ankur, Emmanouil and Michael unravel the potential advantages, challenges and practical realities of using drug-coated balloons in SVD, and the findings of the latest randomised controlled trials studying this area.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology. [Disclaimer: The use of drug-coated balloons in coronay intervention is still off-label; it has not been approved by the FDA.]
We have observed a lot of developments in percutaneous coronary intervention (PCI) over the past 12 months with the publication of various studies and trials. This week, Ankur spoke with J. Dawn Abbott, MD, Associate Professor of Cardiology at Warren Medical School of Brown University about her recently published US Cardiology Review 13.1 article on the significant developments in PCI over the past 12 months.
Dawn is an associate editor of the journal Circulation: Cardiovascular Interventions and is widely known for her research program on PCI and peripheral arterial disease (PAD). Ankur and J. Dawn discuss multiple trials/studies that were published in 2018, including ORBITA, PIONEER-II and ABSORB. J. Dawn also shares her thoughts on the latest stent technologies.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
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Dawn is an associate editor of the journal Circulation: Cardiovascular Interventions and is widely known for her research program on PCI and peripheral arterial disease (PAD). Ankur and J. Dawn discuss multiple trials/studies that were published in 2018, including ORBITA, PIONEER-II and ABSORB. J. Dawn also shares her thoughts on the latest stent technologies.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
This week’s podcast guest needs no introduction! Prof Athena Poppas is one of the most widely known cardiologists in the US and current Vice-President of the American College of Cardiology! Ankur spoke to Athena about her recently published US Cardiology Review 13.1 article on whether early management of hypertension by GPs can improve outcomes.
They discuss the importance of preventative medicine, their experience of reducing hypertension with non-pharmaceutical and pharmaceutical methods, and the significance of the integrated “team approach” when treating comorbid conditions such as hypertension. Athena also shares her thoughts on cardiologists’ responsibility to shape their patients’ lifestyle choices.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
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They discuss the importance of preventative medicine, their experience of reducing hypertension with non-pharmaceutical and pharmaceutical methods, and the significance of the integrated “team approach” when treating comorbid conditions such as hypertension. Athena also shares her thoughts on cardiologists’ responsibility to shape their patients’ lifestyle choices.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Ankur is back with his second #AudioArticle! This week he spoke with Santiago Garcia from the Minneapolis Heart Institute about Santiago’s US Cardiology Review 13.1 article on the role of high-sensitivity cardiac troponin (hscTn) assays and their ability to rapidly rule in or rule out acute coronary syndrome (ACS) with improved sensitivity.
Chest pain is one of the most common reasons for an emergency room visit in the US, with almost 6 million ER visits annually, yet there is no consensus on how to compare the results from various hscTn assays. Tune in to hear Santiago outline the advantages and limitations of using hscTn as a standard biomarket to evaluate patients with suspected ACS in the ER.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
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Chest pain is one of the most common reasons for an emergency room visit in the US, with almost 6 million ER visits annually, yet there is no consensus on how to compare the results from various hscTn assays. Tune in to hear Santiago outline the advantages and limitations of using hscTn as a standard biomarket to evaluate patients with suspected ACS in the ER.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
In this engaging and constructive episode, Nadia recalls her journey to medicine and reflects on the life decisions she had to make along the way: What is the career path that will get us closer to our mission? When is the right time to start family planning? How can we develop resilience in face of rejection? Nadia recalls the conversations with her colleagues and mentors as she progressed in her career. She talks about the practical aspects of tenure track and grant application. Ankur and Nadia discuss the importance of goal setting and exercising a positive mindset.
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In this rich and candid episode, Dr Chakrabarti recalls the early stages of his career and the non-linear route that led to his transition from an interventional cardiologist to working on devices that focus on improving the treatment of deep vein thrombosis (DVT). This journey was paved by self-reflection, hunger for tangible results, and connections with mentors who dared to dream big and wished the same for their mentees.
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Parallax host Dr Ankur Kalra invites Joe Valente, a Board-Certified Patient Advocate (BCPA) and Co-Founder of Team Uncle Joe, to talk about his mission and practical considerations involving CHD care both from a patient and a healthcare provider perspective. In this informative and practical episode, Joe shares details about the process of getting certified as a BCPA and about the work that goes into setting up a non-profit organization. We learn more about how he and his team can support patients with CHD and what he considers to be the pillar of good patient-doctor communication.
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In this week’s Parallax podcast, Dr Ankur Kalra welcomes Dr Rohan Dharmakumar, Executive Director of the Krannert Cardiovascular Research Center at IU School of Medicine, to talk about his research on hemorrhagic myocardial infarction (MI).
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In this week's Parallax, Dr Ankur Kalra is joined by Dr Srihari S Naidu, Director of Cath Labs and Hypertrophic Cardiomyopathy Center at the Westchester Medical Center and President Elect of NY ACC, for an honest conversation on a challenging topic within the cardiology community.
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