EP 97: Conversations about Hypertrophic Cardiomyopathy: Differential Diagnosis, Genetic Testing & Patient-centric Therapy with Dr Owens
In the finale of our series "Conversations about Hypertrophic Cardiomyopathy", Dr Ankur Kalra welcomes, Dr Anjali Tiku Owens, for a dynamic and practical discussion.
Dr Owens is Medical Director of the Center for Inherited Cardiac Disease and Associate Professor of Medicine at the Hospital of the University of Pennsylvania.
This series is supported by an unrestricted educational grant from Bristol Myers Squibb. Please see www.camzyosrems.com for important safety information.
In this week’s episode, Dr Kalra and Dr Owens take us on a journey through the complexities of hypertrophic cardiomyopathy (HCM), with focus on the diagnostic challenges and breakthroughs in this field.
Emphasising with the critical importance of making accurate diagnoses, Dr Owens shares her insights into identifying the common mimickers of HCM through a structured approach starting with taking the patients history.
As the conversation delves deeper, Dr Owens discusses the various diagnostic tools and tests used to rule out other conditions and uncover the underlying aetiology. She navigates us through the algorithm for interpreting genetic test results, differentiating pathogenic variants, benign variants and variants of uncertain significance (VUS). Dr Owens talks about the wider implications for family members and the cases in which she recommends screening.
Dr Kalra asks Dr Owens about her approach to exercise in HCM patients. Additionally, they cover the debated topic of defibrillator therapy and the use of HCM Risk-SCD risk calculator.
Dr Owens provides an overview of the treatment paradigms for HCM, touching on haemodynamic classifications, symptomatology and the evaluation of sudden death risk.
What are the most common mimickers of HCM? What is Dr Owens and her heart team approach to decision making? What is the role of genetic testing in patients with HCM?
This content is intended for US-based physicians.
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This series is supported by an unrestricted educational grant from Bristol Myers Squibb.
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In this week's Parallax, Dr Ankur Kalra welcomes back Dr Jag Singh to discuss Dr Singh's recently published book, "Future Care," which delves into the exciting evolution of medicine over the next 5 to 10 years.
As we adapt to the changes brought about by the pandemic, Dr Singh outlines the necessary steps to foster a reality in which we can utilize these technologies to create more time for human connection.
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As we adapt to the changes brought about by the pandemic, Dr Singh outlines the necessary steps to foster a reality in which we can utilize these technologies to create more time for human connection.
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In 2018, the loss of a friend to suicide compelled Dr Anavekar to embark on a profound journey of contemplative self-exploration. Now, he uses his experience to encourage and guide trainees to pose thought-provoking questions that challenge the status quo of the materialistic approach to medicine, ultimately leading to a more outcome-focused perspective.
What is the Global Cardiology University project? How does Dr Anavekar encourage trainees to re-examine their role in patient care? What is his advice to our listeners?
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What is the Global Cardiology University project? How does Dr Anavekar encourage trainees to re-examine their role in patient care? What is his advice to our listeners?
In the latest episode of Parallax, Dr. Ankur Kalra invites Dr Vijay Rao, the Governor of the Indiana Chapter of the American College of Cardiology, to share his experience and insights with the audience.
As Dr Kalra asks Dr Rao about the ways in which early career faculty members can get involved with the organization at a state level. Dr Rao shares his insider tips and highlights key events where individuals can further their participation.
How can you get involved with your local ACC chapter? How can you improve your leadership skills? What is Dr Rao’s advice for our listeners?
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As Dr Kalra asks Dr Rao about the ways in which early career faculty members can get involved with the organization at a state level. Dr Rao shares his insider tips and highlights key events where individuals can further their participation.
How can you get involved with your local ACC chapter? How can you improve your leadership skills? What is Dr Rao’s advice for our listeners?
Dr Vuyisich shares his personal journey with rheumatoid arthritis and how it led him to explore the intersection of nutrition and the gut microbiome function.
He explains how the complexity of nutrition and the compounds generated by the gut microbiome can impact our health. We learn more about three compounds produced by our gut microbiome that have a strong connection with heart disease.
Through this conversation, Dr Vuyisich invites us to reframe our approach to nutrition and prevention as a question of food education and data-driven science.
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He explains how the complexity of nutrition and the compounds generated by the gut microbiome can impact our health. We learn more about three compounds produced by our gut microbiome that have a strong connection with heart disease.
Through this conversation, Dr Vuyisich invites us to reframe our approach to nutrition and prevention as a question of food education and data-driven science.
In this week’s Parallax Dr Kalra welcomes back Dr Nijjer for their annual review of the most impactful and controversial cardiovascular trials of 2022.
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Neurocardiology refers to the intersection between the fields of neurology and cardiology. The mind and heart are deeply interconnected in terms of anatomy, physiology, and various pathologic states.
This episode features a vascular neurologist and an interventional cardiologist who will discuss the relationship between their two fields of medicine.
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This episode features a vascular neurologist and an interventional cardiologist who will discuss the relationship between their two fields of medicine.
Coming from generations of doctors, Dr Kittleson describes herself first and foremost a dedicated clinician. With her new book, Dr Kittleson offers her mentorship and shares her advice on how to make patient care fulfilling for both clinicians and patients.
In this rich and insightful discussion, Dr Kittleson talks about the origins of famous #kittlesonrules, a collection of tips for doctors shared on Twitter, and her thoughts on mentorship. We learn more about Mastering the Art of Patient Care. Dr Kalra and Dr Kittleson discuss strategies for managing difficult situations in patient care.
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In this rich and insightful discussion, Dr Kittleson talks about the origins of famous #kittlesonrules, a collection of tips for doctors shared on Twitter, and her thoughts on mentorship. We learn more about Mastering the Art of Patient Care. Dr Kalra and Dr Kittleson discuss strategies for managing difficult situations in patient care.
Dr Lawrence Huntoon, Editor-in-Chief of the Journal of the Association of American Physicians and Surgeons, returns for a deep dive into the topic of the hospital peer review system.
What do you need to know about hospital investigations? What is the difference between OPPE and FPPE? How can you get educated on hospital bylaws and processes?
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What do you need to know about hospital investigations? What is the difference between OPPE and FPPE? How can you get educated on hospital bylaws and processes?
In this week’s Parallax Dr Kalra’s guests are the team that fought for justice in Dr Kaki’s case: Dr Lawrence R. Huntoon, Editor-in-Chief of the Journal of the Association of American Physicians and Surgeons and Deborah Gordon, employment attorney.
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Rohin believes that authenticity is one of the keys of his videos’ success. When asked about his journey to medicine he summarises: “I was being rebellious and ended up doing the most cliché job for an Indian possible.” He turns the table and asks Ankur what he think is behind the stereotype of the Indian cardiologist.
Rohin shares an advice that he received at the beginning of his career: “If you can deal with an average day, the exciting day will take care of itself.”
Ankur asks Rohin about Medlife Crisis and the work that goes into producing a show followed by 500K people. Rohin reiterates his passion for research and science communication. Ankur and Rohin discuss what it means to be yourself on social media and what is Rohin’s advice to our early-career listeners.
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Rohin shares an advice that he received at the beginning of his career: “If you can deal with an average day, the exciting day will take care of itself.”
Ankur asks Rohin about Medlife Crisis and the work that goes into producing a show followed by 500K people. Rohin reiterates his passion for research and science communication. Ankur and Rohin discuss what it means to be yourself on social media and what is Rohin’s advice to our early-career listeners.
Year on year, the organisers of the Scientific Sessions aim to give platform to cardiovascular science at its best: innovative, impactful, and collaborative.
In this information-packed episode, Dr Patel takes us behind the scenes and talks about the work that goes into the curation of the programme and the considerations that shape the event. Dr Kalra asks Dr Patel about his highlights over the years and the movement and changes that he observed as vice chair and chair of the event. Dr Patel elaborates on the key late-breaking science trials in 2022. Dr Kalra and Dr Patel discuss the grading system of the award applications and share some useful information with our listeners.
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In this information-packed episode, Dr Patel takes us behind the scenes and talks about the work that goes into the curation of the programme and the considerations that shape the event. Dr Kalra asks Dr Patel about his highlights over the years and the movement and changes that he observed as vice chair and chair of the event. Dr Patel elaborates on the key late-breaking science trials in 2022. Dr Kalra and Dr Patel discuss the grading system of the award applications and share some useful information with our listeners.
Dr Ankur Kalra’s guest this week is Dr Garima Sharma, Director of CardioObstetrics and Assistant Professor of Medicine at the Johns Hopkins University as well as an investigator of the “Global Prevalence and Impact of Hostility, Discrimination, and Harassment in the Cardiology Workplace”.
The American College of Cardiology surveyed cardiologists across the globe to have a more detailed understanding on the impact of hostility, discrimination, and harassment in the workplace. Of almost 6000 cardiologists who took part in the survey 44% reported hostile work environment.
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The American College of Cardiology surveyed cardiologists across the globe to have a more detailed understanding on the impact of hostility, discrimination, and harassment in the workplace. Of almost 6000 cardiologists who took part in the survey 44% reported hostile work environment.
"A failure to finish is a failure to start"
In this week's latest podcast episode, host, Ankur Kalra, MD, meets guest Prof Madhav Swaminathan (Duke University Health System, NC, US) to discuss how he has orchestrated a major humanitarian effort, in association with Duke University Health and The American Society of Echocardiography, to supply ventilation equipment and PPE to hospitals and NGOs during the current COVID-19 crisis in New Delhi, India.
Hear them discuss the challenges and learnings associated with the supply chain, inventory, logistics and cost to deliver this humanitarian effort; which most recently resulted in $140,000 of life-changing equipment being delivered to four key hospitals in New Delhi. A most inspirational episode.
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In this week's latest podcast episode, host, Ankur Kalra, MD, meets guest Prof Madhav Swaminathan (Duke University Health System, NC, US) to discuss how he has orchestrated a major humanitarian effort, in association with Duke University Health and The American Society of Echocardiography, to supply ventilation equipment and PPE to hospitals and NGOs during the current COVID-19 crisis in New Delhi, India.
Hear them discuss the challenges and learnings associated with the supply chain, inventory, logistics and cost to deliver this humanitarian effort; which most recently resulted in $140,000 of life-changing equipment being delivered to four key hospitals in New Delhi. A most inspirational episode.
Over the past two years, Parallax listeners have gotten to know Dr Ankur Kalra through his conversations with our guests. In this episode, we turned the tables and invited CardioNerds co-founder Dr Amit Goyal to reintroduce Dr Ankur Kalra interventional cardiologist, researcher, writer, and the host of this podcast.
In this candid and spiritual conversation Amit and Ankur take a journey through former episodes of Parallax and Ankur’s writings to explore what it takes to strive for a deeper knowledge of ourselves; or, as Ankur puts it, dharma, the inherent order of reality.
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In this candid and spiritual conversation Amit and Ankur take a journey through former episodes of Parallax and Ankur’s writings to explore what it takes to strive for a deeper knowledge of ourselves; or, as Ankur puts it, dharma, the inherent order of reality.
According to Dr Eric Adler, at the core of all impactful research is a powerful narrative that makes us reflect on the human condition. In 2006, when the ground-breaking discovery was made that specialized cells can be turned into stem cells, Dr Eric Adler was thinking about how he could create a synergy between his passion for clinical work and his determination to ask compelling questions in research.
Parallax’s guest this week is Dr Eric David Adler, Medical director of heart transplant and mechanical circulatory support at UC San Diego Health.
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Parallax’s guest this week is Dr Eric David Adler, Medical director of heart transplant and mechanical circulatory support at UC San Diego Health.
Dr Ankur Kalra’s guest is Dr Alin Gragossian, a critical care fellow, heart transplant recipient and advocate. In this episode, Alin talks about her journey as a patient, the psychological aspects of her recovery and her advocacy work. Ankur asks Alin about the mindset behind her sense of purpose and her dedication to help raise awareness of organ donation and young heart failure patients.
How did Dr Gragossian receive her diagnosis? How does she feel about her new reality? What drives her? What is her message to our listeners?
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How did Dr Gragossian receive her diagnosis? How does she feel about her new reality? What drives her? What is her message to our listeners?