EP 97: Conversations about Hypertrophic Cardiomyopathy: Differential Diagnosis, Genetic Testing & Patient-centric Therapy with Dr Owens
In the finale of our series "Conversations about Hypertrophic Cardiomyopathy", Dr Ankur Kalra welcomes, Dr Anjali Tiku Owens, for a dynamic and practical discussion.
Dr Owens is Medical Director of the Center for Inherited Cardiac Disease and Associate Professor of Medicine at the Hospital of the University of Pennsylvania.
This series is supported by an unrestricted educational grant from Bristol Myers Squibb. Please see www.camzyosrems.com for important safety information.
In this week’s episode, Dr Kalra and Dr Owens take us on a journey through the complexities of hypertrophic cardiomyopathy (HCM), with focus on the diagnostic challenges and breakthroughs in this field.
Emphasising with the critical importance of making accurate diagnoses, Dr Owens shares her insights into identifying the common mimickers of HCM through a structured approach starting with taking the patients history.
As the conversation delves deeper, Dr Owens discusses the various diagnostic tools and tests used to rule out other conditions and uncover the underlying aetiology. She navigates us through the algorithm for interpreting genetic test results, differentiating pathogenic variants, benign variants and variants of uncertain significance (VUS). Dr Owens talks about the wider implications for family members and the cases in which she recommends screening.
Dr Kalra asks Dr Owens about her approach to exercise in HCM patients. Additionally, they cover the debated topic of defibrillator therapy and the use of HCM Risk-SCD risk calculator.
Dr Owens provides an overview of the treatment paradigms for HCM, touching on haemodynamic classifications, symptomatology and the evaluation of sudden death risk.
What are the most common mimickers of HCM? What is Dr Owens and her heart team approach to decision making? What is the role of genetic testing in patients with HCM?
This content is intended for US-based physicians.
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This series is supported by an unrestricted educational grant from Bristol Myers Squibb.
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In this week's Parallax, Dr Ankur Kalra welcomes back Dr Jag Singh to discuss Dr Singh's recently published book, "Future Care," which delves into the exciting evolution of medicine over the next 5 to 10 years.
As we adapt to the changes brought about by the pandemic, Dr Singh outlines the necessary steps to foster a reality in which we can utilize these technologies to create more time for human connection.
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As we adapt to the changes brought about by the pandemic, Dr Singh outlines the necessary steps to foster a reality in which we can utilize these technologies to create more time for human connection.
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In this AHA 2021 episode of Parallax, Dr Ankur Kalra’s guest is Dr Amit Khera, Professor and Director of Preventive Cardiology at UT Southwestern Medical Center, Dallas and Vice Chair of the Scientific Sessions. For this week’s show, Dr Khera selected three thought-provoking late-breaking trials that will inform or change clinical practice.
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In this TCT 2021 episode of Parallax, Dr Ankur Kalra’s guest is Prof Mamas Mamas, Consultant Interventional Cardiologist at University Hospitals of North Midlands NHS Trust (UHNM), Professor of Cardiology at Keele University and Senior Clinical Editor of TCTmd.
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In celebration of Diwali, Dr. Ankur Kalra sat down with Dr. Ambarish Pandey, Assistant Professor at The University of Texas Southwestern Medical School, to talk about his career path and the questions that shaped his decision-making over the years.
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This week’s Parallax in collaboration with the Heart Failure Society of America (HFSA) explores the many ways organisations can embrace the needs of a diverse community and create a culture that can react to the realities of patientcare.
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In the second ESC 2021 episode of Parallax, Dr Ankur Kalra’s guest is Dr. Mirvat Alasnag, interventional Cardiologist and Director of Catheterization Laboratory at the King Fahad Armed Forces Hospital (KFAFH) in Saudi Arabia. Dr Alasnag was a programme committee member at this year’s ESC and regional PI of one of the late-breaking trials presented.
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In this special ESC 2021 edition of Parallax, Ankur asks Purvi to review the highlights of the congress. Purvi summarises the design and findings of the trials and their importance in the treatment of patients. Ankur and Purvi discuss how the novel data presented at ESC will inform their practice.
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Dr Ankur Kalra’s guest is Dr Nasrien Ezzeldin Ibrahim, Director of Heart Failure Clinical Research at Inova Heart and Vascular Institute and the writer of SPARKPLUG: The Roadmap to Confidently Ignite and Navigate Your Career Without Compromising Your Dreams.
In this candid episode of Parallax, Nasrien and Ankur open up about their experiences of being an immigrant. Ankur asks Nasrien about her journey to medicine. Nasrien shares the lessons she took away from her years under the mentorship of Dr JoAnn Lindenfeld and later, Dr. James Januzzi. Finally, Nasrien shares her recent experience of writing Sparkplug and how she embraced life with its imperfections and found her purpose.
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In this candid episode of Parallax, Nasrien and Ankur open up about their experiences of being an immigrant. Ankur asks Nasrien about her journey to medicine. Nasrien shares the lessons she took away from her years under the mentorship of Dr JoAnn Lindenfeld and later, Dr. James Januzzi. Finally, Nasrien shares her recent experience of writing Sparkplug and how she embraced life with its imperfections and found her purpose.
This week’s episode starts a series in collaboration with the Heart Failure Society of America (HFSA). Host, Ankur Kalra’s guests are Robert Mentz and Anuradha Lala Senior Editorial Team of the Journal of Cardiac Failure (JCF), the official journal of the HFSA and the Japanese Heart Failure Society (JHFS).
In this practical and insightful episode, Dr Kalra asks what does diversity, equity, inclusion and belonging mean to the editorial board of JCF and what were the steps taken to put these principles into practice.
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In this practical and insightful episode, Dr Kalra asks what does diversity, equity, inclusion and belonging mean to the editorial board of JCF and what were the steps taken to put these principles into practice.
This week, Dr. Ankur Kalra’s guest is Dr. Sameer Bansilal, Executive Director of U.S Medical Affairs of Cardiovascular and Renal at Bayer Pharmaceutical.
Dr. Bansilal was an Assistant Professor of Medicine at the Icahn School of Medicine at Mount Sinai when he decided to seek an alternative pathway to make an impact on patients’ lives.
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Dr. Bansilal was an Assistant Professor of Medicine at the Icahn School of Medicine at Mount Sinai when he decided to seek an alternative pathway to make an impact on patients’ lives.
Early in his career, Dr. Deepak L. Bhatt was considering becoming a basic science researcher. After an exchange with one of his mentors about doing science for the science’s sake, he had a self-realisation: He wanted his work to have a direct impact on patient care.
In the 50th episode of Parallax, Dr. Ankur Kalra’s guest is Dr. Deepak L. Bhatt leading physician, researcher, lecturer, and educator who has authored or co-authored over 1650 publications and was recipient of the ACC’s Distinguished Mentor Award in 2018 and AHA’s Distinguished Scientist Award in 2019.
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In the 50th episode of Parallax, Dr. Ankur Kalra’s guest is Dr. Deepak L. Bhatt leading physician, researcher, lecturer, and educator who has authored or co-authored over 1650 publications and was recipient of the ACC’s Distinguished Mentor Award in 2018 and AHA’s Distinguished Scientist Award in 2019.
How do you nurture resilience in the midst of competition, envy and individualism? What is moral injury? Is the current healthcare landscape driving physicians to burnout? Are we too focused on data and study results? These are some of the questions discussed by Kavitah Chinnaiyan, MD, award winning author and Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI, and host Ankur, in the first episode of this three-part series on burnout and resilience. Send us your thoughts to this episode for Ankur to share in future episodes: pocast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Madhav Swaminathan joins Ankur Kalra for a dynamic conversation about diversity, inclusion and leadership. Madhav shares how, as President of large organisation like the American Society of Echocardiography, he works to create an inclusive platform with opportunities for individuals from diverse backgrounds.
Ankur and Madhav also discuss positive traits of leadership, why we should embrace failure and the importance of mentorship throughout all stages of one’s medical career. Send us your comments to this episode for Ankur to share in future episodes: pocast@radciffe-group.com. Guest @mswami001.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Ankur and Madhav also discuss positive traits of leadership, why we should embrace failure and the importance of mentorship throughout all stages of one’s medical career. Send us your comments to this episode for Ankur to share in future episodes: pocast@radciffe-group.com. Guest @mswami001.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Following the recent controversy surrounding physician portraits displayed in medical hallways, Ankur spoke to Harriette GC Van Spall MD to unpick this hot topic brought back to life by a recent article penned by Jeffrey Flier (former Dean of Harvard Medical School) in The Boston Globe.
Harriette is an Associate Professor of Medicine at the Department of Medicine, Cardiology and the Department of Health Research Methods, Evidence and Impact at McMaster University and the Population Health Research Institute in Hamilton, ON, Canada. In this episode, Ankur and Harriette discuss why this issue is so contentious, what the current state of medical walls represents, why this may be an issue and what alternative medical walls could look like. Harriette also shares her thoughts on how this topic relates to the maintenance of hierarchical power structures in academic institutions, calling for more collaborative leadership and management styles. Guest @hvanspall.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Harriette is an Associate Professor of Medicine at the Department of Medicine, Cardiology and the Department of Health Research Methods, Evidence and Impact at McMaster University and the Population Health Research Institute in Hamilton, ON, Canada. In this episode, Ankur and Harriette discuss why this issue is so contentious, what the current state of medical walls represents, why this may be an issue and what alternative medical walls could look like. Harriette also shares her thoughts on how this topic relates to the maintenance of hierarchical power structures in academic institutions, calling for more collaborative leadership and management styles. Guest @hvanspall.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
In celebration of this month’s ‘National Eat Your Vegetables Day’, this week’s guest is @TheVeggieMD, one of the most prominent physicians on social media! Dr Danielle Belardo MD is a Cardiology Fellow, American Board of Internal Medicine certified and a member of the American College of Cardiology Nutrition and Lifestyle Sub-Committee.
In this episode, Ankur and Danielle speak about the evidence in favour of a whole-food plant-based diet to improve cardiovascular health, the ACC prevention guidelines, how to talk to patients about positive dietary change, the issue of lack of nutrition training in cardiovascular fellowships and what Danielle’s diet looks like as a busy whole-food plant-based cardiology fellow. On her own podcast ‘Nutrition Rounds’ Danielle has discussions about evidence-based plant-based nutrition with physicians who are leading experts in nutrition and health.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
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In this episode, Ankur and Danielle speak about the evidence in favour of a whole-food plant-based diet to improve cardiovascular health, the ACC prevention guidelines, how to talk to patients about positive dietary change, the issue of lack of nutrition training in cardiovascular fellowships and what Danielle’s diet looks like as a busy whole-food plant-based cardiology fellow. On her own podcast ‘Nutrition Rounds’ Danielle has discussions about evidence-based plant-based nutrition with physicians who are leading experts in nutrition and health.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Listen to our first episode with two guests! Ankur spoke with Emmanouil S Brilakis, MD and Michael Megaly, MD from the Minneapolis Heart Institute, Abbott Northwestern Hospital about their article on the role of drug-coated balloons in small-vessel coronary artery disease (SVD) published in US Cardiology Review 13.1. Percutaneous coronary intervention of SVD remains challenging due to difficulties with device delivery and high restenosis rate, making drug-coated balloons an attractive emerging option in patients with SVD.
In this brilliant conversation, Ankur, Emmanouil and Michael unravel the potential advantages, challenges and practical realities of using drug-coated balloons in SVD, and the findings of the latest randomised controlled trials studying this area.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology. [Disclaimer: The use of drug-coated balloons in coronay intervention is still off-label; it has not been approved by the FDA.]
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In this brilliant conversation, Ankur, Emmanouil and Michael unravel the potential advantages, challenges and practical realities of using drug-coated balloons in SVD, and the findings of the latest randomised controlled trials studying this area.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology. [Disclaimer: The use of drug-coated balloons in coronay intervention is still off-label; it has not been approved by the FDA.]