EP 111: ACC 24 in Review With Dr Vallabhajosyula: 5 Trials That Will Change Your Practice
Dr Ankur Kalra’s guest this week is Dr Saraschandra Vallabhajosyula, Interventional and Critical Care Cardiologist, Assistant Professor of Medicine at the Warren Alpert Medical School of Brown University and the Director of the Cardiac Intensive Care Unit at Rhode Island Hospital, the Miriam Hospital and Lifespan Cardiovascular Institute. In this episode of Parallax, they delve into the latest insights from ACC.24 through the lens of five pivotal late-breaking trials.
Dr Vallabhajosyula offers a deep dive into the nuances of each study. Together, Dr Kalra and Dr Vallabhajosyula distil the complexities of these trials into key messages for practice, grounded in their own clinical experiences.
In the spotlight are five key trials:
1. DanGer Shock: Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock
2. RELIEVE-HF: Safety and effectiveness of the V-Wave® Ventura® Interatrial Shunt for the treatment of heart failure (HF)
3. PREVENT: Preventive PCI or medical therapy alone for vulnerable atherosclerotic coronary plaque
4. REDUCE AMI: Decreased usage of beta-blockers after acute myocardial infarction
5. ORBITA-COSMIC: Coronary sinus reducer for the treatment of refractory angina
Dr Kalra and Dr Vallabhajosyula dissect the practical implications of these trials, answering pressing questions and addressing emerging dilemmas. What are the key takeaways from ACC.24? How do these findings shape contemporary clinical practice?
Questions and comments can be sent to “podcast@radcliffe-group.com” and may be answered by Ankur in the next episode.
Guest: @SarasVallabhMD Host: @AnkurKalraMD and produced by: @RadcliffeCARDIO
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Tune in for a rich discussion with Dr Jonathan Fisher and Dr Ankur Kalra on the future of healthcare, well-being, and rediscovering the human connection at the heart of medicine. Find out more about the bestselling book Just One Heart: A Cardiologist’s Guide to Healing, Health, and Happiness.
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The first female cardiac surgeon qualified in the 1960’s. Today there are only 4.5% women in cardiology and only 4% in thoracic surgery. Ankur Kalra meets with Dr Kendra Grubb, the first women to be trained at the University of Virginia, US, on cardiothoracic surgery and the 250th board certified women in thoracic surgery.
Her recent post on social media went viral. It was a photo of an all-women surgical team carrying out a complex structural heart procedure. It had over 100,000 views and was seen by people in over 75 different countries. It’s clear from this online reaction, that now is the time for women to be recognised for the work they are doing in medicine.
Listen to this engaging discussion between them on the challenges of being a woman in cardiovascular medicine today.
Submit your question to Ankur via: podcast@radciffe-group.com. Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Her recent post on social media went viral. It was a photo of an all-women surgical team carrying out a complex structural heart procedure. It had over 100,000 views and was seen by people in over 75 different countries. It’s clear from this online reaction, that now is the time for women to be recognised for the work they are doing in medicine.
Listen to this engaging discussion between them on the challenges of being a woman in cardiovascular medicine today.
Submit your question to Ankur via: podcast@radciffe-group.com. Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
In our final episode of the year, Ankur has an long conversation with Sukh Nijjer from Imperial College London about the most impactful, exciting and controversial clinical trials of 2019. Sukh and Ankur also discuss how these trials might change practice in the future, and how practice patterns and decisions differ between the US and the UK. In light of an emerging trend of shared decision making between physicians of different specialities and patients with a vast amount of information at their fingertips, Sukh and Ankur examine what tools they use to reconcile the growing data from clinical trials.
Trials discussed in detail include those presented at the ACC in New Orleans: PARTNER 3 & Evolut Low Risk on TAVR/TAVI, and SAFARI & COAPT on radial vs femoral access; presented at the ESC in Paris: THEMIS and ISAR-REACT 5 on DAPT post-PCI, DAPA-HF on SGLT2i’s for heart failure, and COMPLETE on PCI of non-culprit lesions in STEMI; presented at TCT in San Francisco: TWILIGHT on DAPT post-PCI, and EXCEL at 5 years on PCI vs CABG in left main CAD; and finally, presented at AHA in Philadelphia: ISCHEMIA on medical vs invasive approaches in ischemic events. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Trials discussed in detail include those presented at the ACC in New Orleans: PARTNER 3 & Evolut Low Risk on TAVR/TAVI, and SAFARI & COAPT on radial vs femoral access; presented at the ESC in Paris: THEMIS and ISAR-REACT 5 on DAPT post-PCI, DAPA-HF on SGLT2i’s for heart failure, and COMPLETE on PCI of non-culprit lesions in STEMI; presented at TCT in San Francisco: TWILIGHT on DAPT post-PCI, and EXCEL at 5 years on PCI vs CABG in left main CAD; and finally, presented at AHA in Philadelphia: ISCHEMIA on medical vs invasive approaches in ischemic events. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Recorded before the American Heart Association (AHA) Scientific Sessions 2019, Ankur is joined by Rasha K Al-Lamee, Interventional Cardiologist at Imperial College Healthcare NHS Trust in London and Study Director of the Objective Randomised Blinded Investigation with Optimal Medical Therapy of Angioplasty in Stable Angina (ORBITA) trial. Rasha talks about how she got into academia, the significance of her end-of-training PhD, and what led to the genesis of ORBITA.
Ankur and Rasha also discuss the findings and unanswered questions of ORBITA, and how recent research in coronary revascularisation and stable ischemic heart disease has (or has not) changed their clinical practice. Finally, in anticipation of its presentation at AHA 2019, Rasha gives an overview of the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA). Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Ankur and Rasha also discuss the findings and unanswered questions of ORBITA, and how recent research in coronary revascularisation and stable ischemic heart disease has (or has not) changed their clinical practice. Finally, in anticipation of its presentation at AHA 2019, Rasha gives an overview of the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA). Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
In Episode 16, Ankur spoke with Ajay J Kirtane on why he became a cardiologist, how he fell into academic research, and why the cardiology specialty is heavy with people of Indian origin.
Ajay also talks about how he has negotiated between competing priorities in clinical and academic work, and how he manages fatherhood with a busy career. Ahead of the American Heart Association Scientific Sessions 2019, Ajay also shared what he thinks we can expect from the highly anticipate ISCHEMIA trial. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Ajay also talks about how he has negotiated between competing priorities in clinical and academic work, and how he manages fatherhood with a busy career. Ahead of the American Heart Association Scientific Sessions 2019, Ajay also shared what he thinks we can expect from the highly anticipate ISCHEMIA trial. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
How did Gregg from Cleveland, Ohio become Gregg W Stone MD, world-leading interventional cardiologist and clinical trialist? This week, Ankur had the pleasure of speaking to Gregg about his personal and professional journey through the ‘golden years’ of interventional cardiology.
Gregg also shares his tips on how to progress from clinical practice to academic research, and what it takes to be a successful clinical investigator. Finally, Gregg shares with Ankur what personality traits he looks for in mentees and why presenting a final project is not enough. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Gregg also shares his tips on how to progress from clinical practice to academic research, and what it takes to be a successful clinical investigator. Finally, Gregg shares with Ankur what personality traits he looks for in mentees and why presenting a final project is not enough. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Recorded on site at TCT, COAPT investigator Dr Neal Kleiman and Ankur discuss the realities of establishing an academic career as an interventional cardiologist. Neal explains why it is important to wear multiple hats and balance academia with a clinical presence.
Digging more into the practicalities of everyday work-life, Neal reflects on the challenges of reporting to multiple bosses who have different goals, and how geography enabled him to move between cathlab and academia. Neal also shares what he looks for in early career academic cardiologists. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Digging more into the practicalities of everyday work-life, Neal reflects on the challenges of reporting to multiple bosses who have different goals, and how geography enabled him to move between cathlab and academia. Neal also shares what he looks for in early career academic cardiologists. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Hari joins Ankur for a second episode to share his tips on how to maintain a healthy work-life balance as an ambitious cardiologist and his key tips of cultivating a career in leadership positions. What ‘makes’ balanced work versus balanced life? Should the two overlap and if yes, how much? How do you prioritise ‘life’ when trying to build a career? Do you really need to become an expert in multitasking? What’s the key to managing a team effectively and successfully?
Ahead of TCT 2019, Ankur and Hari also talk about which trials presented in San Francisco they are most excited about! Submit your question to Ankur via: podcast@radciffe-group.com. Guest @SrihariNaiduMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Ahead of TCT 2019, Ankur and Hari also talk about which trials presented in San Francisco they are most excited about! Submit your question to Ankur via: podcast@radciffe-group.com. Guest @SrihariNaiduMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
In this episode, Srihari S Naidu shares his career tips for young, ambitious cardiologists and what he has learnt about mentorship from his numerous leadership positions. Hari elaborates on the different types of mentorship, the importance of developing non-academic skills, why you should focus on your strengths rather than weaknesses, and the fickle art of managing one’s public/private personas as a young cardiologist in an era of social media.
Having recently applied for the programme himself, Ankur also speaks with Hari about the history, purpose and future of the Society for Cardiovascular Angiography and Interventions (SCAI) Emerging Leader Mentorship (ELM) Fellowship Programme. Submit your question to: podcast@radciffe-group.com. Guest @SrihariNaiduMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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Having recently applied for the programme himself, Ankur also speaks with Hari about the history, purpose and future of the Society for Cardiovascular Angiography and Interventions (SCAI) Emerging Leader Mentorship (ELM) Fellowship Programme. Submit your question to: podcast@radciffe-group.com. Guest @SrihariNaiduMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
What are the key pillars of self-care and what do dirty windshields have to do with it? How can you take meditation “off the matt”? What has chronobiology and Ayurveda taught us about working with, rather than against, our circadian rhythm?
In the final episode of our burnout and resilience series, Kavitha and Ankur give you some practical tools of self-care to help you avoid burnout. Kavitah Chinnaiyan, MD, is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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In the final episode of our burnout and resilience series, Kavitha and Ankur give you some practical tools of self-care to help you avoid burnout. Kavitah Chinnaiyan, MD, is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
What does mindfulness have to do with burnout? Is our definition of success driving our stress and anxiety? How can we channel our ego into something positive?
In our second episode on burnout and resilience, Kavitah Chinnaiyan, MD, and Ankur take a deeper dive into mindfulness and training the brain to move from Default-Mode to Task-Positive Networks. Kavitah is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
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In our second episode on burnout and resilience, Kavitah Chinnaiyan, MD, and Ankur take a deeper dive into mindfulness and training the brain to move from Default-Mode to Task-Positive Networks. Kavitah is an award-winning author and, Cardiologist and Director of Cardiac CT Research at Beaumont Health, MI. Send us your thoughts to this episode for Ankur to share in future episodes: podcast@radciffe-group.com. Guest @ChinnaiyanMD.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
In the early days of the Black Lives Matter movement, a group of internal medicine residents posed a question: What can we do about racial disparity within our institution?
Brigham and Women’s Hospital’s Health Equity Committee decided to confront the status quo by asking: How is racism on a structural level present within our walls?
Ankur Kalra’s guests Michelle Morse (Founding Co-Director of EqualHealth and Assistant Professor at Harvard Medical School) and Lauren Eberly (Cardiology Fellow at the University of Pennsylvania) are co-authors of a retrospective study that demonstrated what had previously only been observed: That black or brown heart failure patients ended up in general medicine rather than specialised cardiology services. Following the publication of the study in November 2019, the Health Equity Committee started to roll out anti-racism trainings and to work on objective admission guidelines to mitigate biased behaviours.
Aarti Bhatt (Assistant Professor of Medicine at the University of Minnesota), member of the Minnesota chapter of Campaign Against Racism, talks about their initiative to support projects that have a positive impact on local communities on a global scale.
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Brigham and Women’s Hospital’s Health Equity Committee decided to confront the status quo by asking: How is racism on a structural level present within our walls?
Ankur Kalra’s guests Michelle Morse (Founding Co-Director of EqualHealth and Assistant Professor at Harvard Medical School) and Lauren Eberly (Cardiology Fellow at the University of Pennsylvania) are co-authors of a retrospective study that demonstrated what had previously only been observed: That black or brown heart failure patients ended up in general medicine rather than specialised cardiology services. Following the publication of the study in November 2019, the Health Equity Committee started to roll out anti-racism trainings and to work on objective admission guidelines to mitigate biased behaviours.
Aarti Bhatt (Assistant Professor of Medicine at the University of Minnesota), member of the Minnesota chapter of Campaign Against Racism, talks about their initiative to support projects that have a positive impact on local communities on a global scale.
Heart surgery is not the best option for every patient suffering from structural heart disease. This was recognized by interventional cardiologist Anmar Kanaa’N and cardiac surgeon Joseph Lahorra who decided to unify their skillsets and bring the Structural Heart Program to life. Their vision was to offer patients with heart valve diseases all available options at Cleveland Clinic’s Akron General.
In this week’s Parallax, Dr Kanaa’N, the director of the program, and Dr Lahorra, chairman of the Heart, Vascular & Thoracic Department of Akron General introduce the listeners to the foundations of their program and the paradigm shift brought by TAVR.
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In this week’s Parallax, Dr Kanaa’N, the director of the program, and Dr Lahorra, chairman of the Heart, Vascular & Thoracic Department of Akron General introduce the listeners to the foundations of their program and the paradigm shift brought by TAVR.
The State of Ohio reported its first coronavirus cases on March 9. Prior to that, on February 28, the Cleveland Clinic announced that they are prepared to open 1,000 additional hospital beds if needed. Ohio was one of the states to follow recommendations and intervene quickly.
Ankur Kalra asks Grant W Reed, Director of the Cleveland Clinic’s STEMI program, to reflect on the actions they took and the challenges of delaying cardiovascular procedures in the wake of the coronavirus pandemic. Dr Reed offers insight on the factors that influenced the Cleveland Clinic’s STEMI policy for COVID-19. Ankur and Grant discuss the triage considerations for patients with structural heart disease and the steps the clinic took to protect its healthcare workers.
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Ankur Kalra asks Grant W Reed, Director of the Cleveland Clinic’s STEMI program, to reflect on the actions they took and the challenges of delaying cardiovascular procedures in the wake of the coronavirus pandemic. Dr Reed offers insight on the factors that influenced the Cleveland Clinic’s STEMI policy for COVID-19. Ankur and Grant discuss the triage considerations for patients with structural heart disease and the steps the clinic took to protect its healthcare workers.
Lisa Rosenbaum has been writing extensively about the human face of medicine. Her articles have been widely circulated by publications like The New York Times, The New Yorker and The New England Journal of Medicine.
In this edition of Parallax Dr Kalra asked Dr Rosenbaum about the influences that shaped her choices as a writer and as a healthcare professional. Dr Rosenbaum opens up about her childhood and how she connected to her grandfather through writing and medicine. We learn about Lisa’s first day at medical school and her latest writing project.
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In this edition of Parallax Dr Kalra asked Dr Rosenbaum about the influences that shaped her choices as a writer and as a healthcare professional. Dr Rosenbaum opens up about her childhood and how she connected to her grandfather through writing and medicine. We learn about Lisa’s first day at medical school and her latest writing project.
A week after Jag Singh had tested positive for 2019-nCoV, he became a patient in his hospital’s intensive care unit. This week he joins Ankur Kalra, MD to tell us about his journey as a clinician-scientist.
Jagmeet P Singh, associate chief of the cardiology division at Massachusetts General Hospital and professor of medicine at Harvard Medical School joins Ankur Kalra for a deep conversation about his journey across three continents. Dr Singh talks about the importance of choosing fulfilment over success. We gain more insights on the recent late-breaking trial, MADIT-CHIC focusing on cardiac resynchronization therapy. Ankur asks Jag about his experience of being on the other side of the healthcare system and his enrolment in the since halted remdesivir trial.
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Jagmeet P Singh, associate chief of the cardiology division at Massachusetts General Hospital and professor of medicine at Harvard Medical School joins Ankur Kalra for a deep conversation about his journey across three continents. Dr Singh talks about the importance of choosing fulfilment over success. We gain more insights on the recent late-breaking trial, MADIT-CHIC focusing on cardiac resynchronization therapy. Ankur asks Jag about his experience of being on the other side of the healthcare system and his enrolment in the since halted remdesivir trial.