![EP 46 Dr Eric Adler on Mission, Mentorship & Synergy Between Research & Patient Care](https://assets.radcliffecardiology.com/s3fs-public/podcast/2024-03/ep_46.png?VersionId=MSzaseztIWKC1.DamN6s0QAfE8BfpY03)
According to Dr Eric Adler, at the core of all impactful research is a powerful narrative that makes us reflect on the human condition. In 2006, when the ground-breaking discovery was made that specialized cells can be turned into stem cells, Dr Eric Adler was thinking about how he could create a synergy between his passion for clinical work and his determination to ask compelling questions in research.
Dr Adler embarked on this question when a patient died unexpectedly and Dr Stacey Clegg, a fellow working with Dr Adler, grew the cells and discovered that the patient suffered from a devastating multisystemic disorder called Danon disease. Today the new gene therapy that his team developed is on clinical trial.
Parallax’s guest this week is Dr Eric David Adler, Medical director of heart transplant and mechanical circulatory support at UC San Diego Health. In this in-depth episode, Ankur and Eric reflect on the decisions that had to be made in the early stages of their career. Eric shares the lessons he took away from the mentorship of Dr Joseph Loscalzo, Dr Valentin Fuster and many others. Eric talks about his research, clinical work and the future of gene therapy.
What are the pivotal moments of the journey of Eric Adler? What keeps him motivated? How can he balance between patient care and research? What is his message to our listeners at the beginning of their career?
Questions and comments can be sent to “podcast@radciffe-group.com” and may be answered by Ankur in the next episode. Guest @EricAdler17, hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Brought to you by Edwards.
![Brought to you by Edwards: www.edwardstavr.com](https://assets.radcliffecardiology.com/article/2024-03/edwards_logo_v2_423_rgb_pos_jpg_16.jpg?VersionId=xPH_LUnHYg1GVjvQS03ceTuwJpeMsEky)
Brought to you by Edwards: www.edwardstavr.com
![EP 47 CardioNerds Meets Parallax: An Examined Life with Dr Ankur Kalra, Cardiologist, Writer & Podcaster](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax_Ep47_Banner1.png?VersionId=H.kBPu1Ny3X69ncOAnG4gWlQb3HpGg8B&itok=UJ65aKYO)
In this candid and spiritual conversation Amit and Ankur take a journey through former episodes of Parallax and Ankur’s writings to explore what it takes to strive for a deeper knowledge of ourselves; or, as Ankur puts it, dharma, the inherent order of reality.
![Clinician-Scientist During The COVID-19 Pandemic](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-Ep-25-Final-Artwork.jpeg?VersionId=cwVToZRgmSX_WV6ohQzoMI83trsZcbJG&itok=Zim367CL)
Jagmeet P Singh, associate chief of the cardiology division at Massachusetts General Hospital and professor of medicine at Harvard Medical School joins Ankur Kalra for a deep conversation about his journey across three continents. Dr Singh talks about the importance of choosing fulfilment over success. We gain more insights on the recent late-breaking trial, MADIT-CHIC focusing on cardiac resynchronization therapy. Ankur asks Jag about his experience of being on the other side of the healthcare system and his enrolment in the since halted remdesivir trial.
![COVID-19 Lessons Learnings From Italy](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-Ep-24-Final-Artwork.jpeg?VersionId=TOHaEyTtUUS7PyGmm8gqp89VQTxGGjRn&itok=yN7RJsmR)
Prof Michele Senni is Director of Cardiology at Papa Giovanni XXIII Hospital, Bergamo Italy. He contracted COVID-19 himself and in this latest podcast he meets with Ankur Kalra, MD to discuss his personal experience in dealing with patients and COVID-19 in Europe’s outbreak epicentre.
Hear them discuss the burden on healthcare, patient selection, the importance of testing and PPE and how COVID has resulted in a reduction of acute myocardial infarction and heart failure in patients.
![23: COVID-19 And Cardiovascular Disease](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-Ep-23-Final-Artwork.jpeg?VersionId=DqmVBCmA7JeTgNiFplUusTJf_O15Friu&itok=MYGGjJ1T)
In this latest episode, Ankur Kalra, MD meets with Andrew Sauer, MD, co-author of an upcoming paper in US Cardiology Review on COVID-19 and Cardiovascular Disease that provides a concise and current summary of cardiovascular complications from COVID-19.
Hear them discuss the latest issues surrounding the pandemic, the known cardiac implications and the rapidly emerging data.
![22: COVID-19 Lessons and Learnings From South East Asia](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-Ep-22-Final-Artwork.jpeg?VersionId=rry27d85gaZih32Wtuaz.f7OqT5wXD2I&itok=gHsosyDd)
Hear Bill’s take on how East Asia responded to and successfully managed the pandemic and how they are now seeing a significant reduction in cases outside the epicentre. Hear how the strategy resulted in only 93 patients in Bill’s city of Nanjing, testing positive for coronavirus with a city population of 8 million.
Learn about effective responses, the importance of early control and how as a cardiovascular physician, your life and practice may be impacted by the virus.
Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
![21: The “Interventional Intensivist” With Ann Gage](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-Ep-21-Twitter.jpeg?VersionId=.m79HJOc7uTd_a2TAYs4XfLoGvw4hC51&itok=aMFrUc-u)
In this episode Ankur Kalra, MD meets with Dr Ann Gage, Cleveland Clinic’s first ‘interventional intensivist’. She discusses her unique skill set, what it means to be an interventionalist in the cath lab but also an expert in cardiovascular intensive care and advocates why such a unique skill set and critical care training are required in today’s modern medicine.
Listen to this engaging discussion between them on the challenges of being a woman in cardiovascular medicine today.
Submit your question to Ankur via: podcast@radciffe-group.com. Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
![Staging Of Aortic Valve Disease: A Novel Approach](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-Ep-20-Final-Artwork_LN.png?VersionId=PNest2ZDAjW.pMwBN.HUy8DYLuQFebK2&itok=XlmL6a9O)
Listen to this, as well as an overview on his interesting childhood and his views on the future of cardiac imaging to treat TAVR.
Submit your question to Ankur via: podcast@radciffe-group.com. Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
![19: Women In Cardiology With Kendra Grubb](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-Ep-19-T-1200x628-twitter-Card.jpeg?VersionId=1_x2j13muJp536QAVoHElSPyhVGTgsFM&itok=4FKsupVl)
Her recent post on social media went viral. It was a photo of an all-women surgical team carrying out a complex structural heart procedure. It had over 100,000 views and was seen by people in over 75 different countries. It’s clear from this online reaction, that now is the time for women to be recognised for the work they are doing in medicine.
Listen to this engaging discussion between them on the challenges of being a woman in cardiovascular medicine today.
Submit your question to Ankur via: podcast@radciffe-group.com. Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
![18: The Year 2019 In Review With Sukh Nijjer](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-w-Sukhjinder-Nijjer.png?VersionId=JTTB5Vv64hUNWcZfgTHUl0d_TqWqBpcD&itok=S8YyqYye)
Trials discussed in detail include those presented at the ACC in New Orleans: PARTNER 3 & Evolut Low Risk on TAVR/TAVI, and SAFARI & COAPT on radial vs femoral access; presented at the ESC in Paris: THEMIS and ISAR-REACT 5 on DAPT post-PCI, DAPA-HF on SGLT2i’s for heart failure, and COMPLETE on PCI of non-culprit lesions in STEMI; presented at TCT in San Francisco: TWILIGHT on DAPT post-PCI, and EXCEL at 5 years on PCI vs CABG in left main CAD; and finally, presented at AHA in Philadelphia: ISCHEMIA on medical vs invasive approaches in ischemic events. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
![Rasha Al-Lamee On ORBITA, ISCHEMIA, Coronary Revascularisation](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-w-Rasha-Al-Lamee.png?VersionId=HJSxV4uQ5EEPiuGn1o7Vr68p0IOt2DhX&itok=cZhcfzUv)
Ankur and Rasha also discuss the findings and unanswered questions of ORBITA, and how recent research in coronary revascularisation and stable ischemic heart disease has (or has not) changed their clinical practice. Finally, in anticipation of its presentation at AHA 2019, Rasha gives an overview of the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA). Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
![Ajay J Kirtane On Fatherhood, Cardiology, Research & Even A Little Karma Yoga](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax-Podcast-w-Ajay-J-Kirtane.png?VersionId=hQIDUcD1vBYgWpnRPihH.rQKqykSYzUC&itok=6M8-g4r0)
Ajay also talks about how he has negotiated between competing priorities in clinical and academic work, and how he manages fatherhood with a busy career. Ahead of the American Heart Association Scientific Sessions 2019, Ajay also shared what he thinks we can expect from the highly anticipate ISCHEMIA trial. Submit your question to Ankur via: podcast@radciffe-group.com.
Hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
![40: Mentorship, Reflection & the Journey of Mandeep R Mehra](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax%20Podcast%20Ep%2040%20Final%20Artwork.jpeg?VersionId=8fvVY219S6dLlbaUbbQVdESnvZmk7JB0&itok=T1HXtY2c)
In this week’s episode Ankur’s guest is Dr Mandeep R Mehra, Medical Director of Brigham Heart and Vascular Center and Professor of Medicine at Harvard Medical School.
![EP 39: The Year 2020 in Review with Sukh Nijjer](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax_39_1200.jpeg?VersionId=JU1Gu8abffSo_fwsmEhL5s9f7I0rM30L&itok=boZinKUo)
Which COVID19 patients require risk stratification with a stress test? What are the take-home messages for physicians taking care of patients diagnosed with COVID19? What were the key trials of 2020? What can we learn from the negative results of the STRENGHT study? How have studies like STOP-AF influenced clinical practice?
![38: Martin B Leon on CRF, Mentorship and the Lessons of 2020](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax_38-2.jpeg?VersionId=T6upLePKIpYZ8wBmEH9dkg65vQvHOFiZ&itok=990rBdAf)
What makes Dr Martin B Leon tick? What is his message to cardiologists and/or researchers at the beginning of their careers? How did the pandemic and his work as a clinician in New York change his perspective?
![37: Lindsay’s Law: From Ballerina to Health Advocate](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax_37.jpeg?VersionId=O1.0MQFT2P0xtVa5F3cpEE6jfvnmYcWO&itok=NmREiPwF)
In this episode Ankur asks Lindsay about her treatment path. Lindsay recalls her own journey to taking control of her condition and the important role of information in patient adherence. Lindsay, former Miss Ohio, talks how she used the pageant to create awareness. Lindsay talks about work in state legislation and her plans for 2021.
![WiC, Mentorship and Diversity in Academic Publishing](https://assets.radcliffecardiology.com/s3fs-public/styles/podcast_episode_teaser/public/podcast-episode/2024-02/Parallax_362.jpeg?VersionId=g6awb.OYio50oxPdztK5P0q39ElFjL.3&itok=RzaRIq05)
US Cardiology Review journal, has recently seen a 7-fold increase in female editorial board members in response to journal-based strategic initiatives and the stellar work of USC editorial board leadership, Ankur Kalra (Editor in Chief) and Bill Gogas (Deputy Editor in Chief), who were keen to drive this change. With thanks to Dr Anastasia Mihailidou’s tenure as a new board member and her suggested nominees, ten new female board members have recently joined US Cardiology Review’s editorial board.