Navigating HCM Management Paradigms with Dr Masri
EP 96: Conversations about Hypertrophic Cardiomyopathy: Navigating HCM Management Paradigms with Dr Masri

Average (ratings)
No ratings
 
  Your rating

In the second episode of our mini-series "Conversations about Hypertrophic Cardiomyopathy", Dr Ankur Kalra sat down with Dr Ahmad Masri to have a deep-dive into the management paradigms of hypertrophic cardiomyopathy (HCM), considering the evolution of medical therapy in recent years. Dr Ahmad Masri is a Cardiologist and the Director of OHSU Hypertrophic Cardiomyopathy Center.

 

This series is supported by an unrestricted educational grant from Bristol Myers Squibb. Please see www.camzyosrems.com for important safety information.

 

Dr Kalra invites Dr Masri to guide us through his decision-making process in evaluating medical and surgical options in patients with obstructive hypertrophic cardiomyopathy. Dr Masri delves into first and second-line treatment strategies while exploring the significance of FDA-approved cardiac myosin inhibitors in the management of hypertrophic cardiomyopathy. Dr Kalra asks Dr Masri about the practical office-based clinical course for patients deemed suitable candidates to receive mavacamten. Dr Masri provides a clear and practical outline of what it entails to opt for this second-line medical therapy including the REMS programme required for therapy (www.camzyosrems.com). Dr Masri highlights the importance of looking at HCM patients holistically to find the treatment which best fits their circumstances and preferences in choosing surgical and medical therapy options.

 

What are the available management options for patients with HCM? How does Dr Masri approach shared decision-making in the management of HCM? What are some of the practical considerations regarding the cardiac myosin inhibitor, mavacamten?

 

This content is intended for US-based physicians.


Read MoreRead Less
Share

This series is supported by an unrestricted educational grant from Bristol Myers Squibb.

Read MoreRead Less
Up Next
Differential Diagnosis, Genetic Testing & Patient-centric Therapy
EP97 • Aug 07, 2023 • 44m 40s
In the finale of our series "Conversations about Hypertrophic Cardiomyopathy", Dr Ankur Kalra welcomes, Dr Anjali Tiku Owens, for a dynamic and practical discussion.

Dr Owens is Medical Director of the Center for Inherited Cardiac Disease and Associate Professor of Medicine at the Hospital of the University of Pennsylvania.

This series is supported by an unrestricted educational grant from Bristol Myers Squibb. Please see www.camzyosrems.com for important safety information.

This content is intended for US-based physicians.
Read More
All Episodes
EP 48: Supporting India During COVID: Prof Madhav Swaminathan, Duke Health and ASE Humanitarian Aid
EP48 • May 17, 2021 • 40m 3s
"A failure to finish is a failure to start"

In this week's latest podcast episode, host, Ankur Kalra, MD, meets guest Prof Madhav Swaminathan (Duke University Health System, NC, US) to discuss how he has orchestrated a major humanitarian effort, in association with Duke University Health and The American Society of Echocardiography, to supply ventilation equipment and PPE to hospitals and NGOs during the current COVID-19 crisis in New Delhi, India.

Hear them discuss the challenges and learnings associated with the supply chain, inventory, logistics and cost to deliver this humanitarian effort; which most recently resulted in $140,000 of life-changing equipment being delivered to four key hospitals in New Delhi. A most inspirational episode.
Read More
EP 47 CardioNerds Meets Parallax: An Examined Life with Dr Ankur Kalra, Cardiologist, Writer & Podcaster
EP47 • May 03, 2021 • 1h 8m 3s
Over the past two years, Parallax listeners have gotten to know Dr Ankur Kalra through his conversations with our guests. In this episode, we turned the tables and invited CardioNerds co-founder Dr Amit Goyal to reintroduce Dr Ankur Kalra interventional cardiologist, researcher, writer, and the host of this podcast.
In this candid and spiritual conversation Amit and Ankur take a journey through former episodes of Parallax and Ankur’s writings to explore what it takes to strive for a deeper knowledge of ourselves; or, as Ankur puts it, dharma, the inherent order of reality.
Read More
EP 46 Dr Eric Adler on Mission, Mentorship & Synergy Between Research & Patient Care
EP46 • Apr 19, 2021 • 1h 6s
According to Dr Eric Adler, at the core of all impactful research is a powerful narrative that makes us reflect on the human condition. In 2006, when the ground-breaking discovery was made that specialized cells can be turned into stem cells, Dr Eric Adler was thinking about how he could create a synergy between his passion for clinical work and his determination to ask compelling questions in research.

Parallax’s guest this week is Dr Eric David Adler, Medical director of heart transplant and mechanical circulatory support at UC San Diego Health.
Read More
EP 45: The Journey of Dr Alin Gragossian, Physician, Heart Transplant Recipient & Advocate
EP45 • Apr 05, 2021 • 36m 46s
Dr Ankur Kalra’s guest is Dr Alin Gragossian, a critical care fellow, heart transplant recipient and advocate. In this episode, Alin talks about her journey as a patient, the psychological aspects of her recovery and her advocacy work. Ankur asks Alin about the mindset behind her sense of purpose and her dedication to help raise awareness of organ donation and young heart failure patients.

How did Dr Gragossian receive her diagnosis? How does she feel about her new reality? What drives her? What is her message to our listeners?
Read More
EP 44: Refugee, Dishwasher, Cardiologist, Humanitarian: The Journey of Dr H
EP44 • Mar 22, 2021 • 46m 8s
How can we use our power and privilege to serve? How did his experiences shape Dr Kelli to become an ambassador for his community? What is his message to our listeners?
Just after 9/11, Heval, the 18-year-old Syrian Kurdish refugee found a job as a dishwasher. At this point, he was the sole provider of his family. The pressure that comes from being poor did not leave him for many years. Today, he is firm believer in giving back to underserved communities by spreading awareness within the medical community. As he says, well-meaning people of privilege are sometimes afraid to act. What we need is more people to bridge the gap and find ways to help each other.
Read More
EP 43: Dr Nishtha Sodhi on Mentorship, Innovation and Inclusivity
EP43 • Mar 08, 2021 • 47m 20s
Dr Sodhi remembers the first time she stepped into a Cath lab and found her passion. Years later she was preparing to do a complex TAVR procedure with her colleagues when suddenly they all recognised the significance of four women coming together in the lab. The photo of the four of them was shared widely on social media. For Dr Sodhi it became a symbol of what great mentorship can achieve, and for many others it is a beacon of hope.
What drives Dr Nishtha Sodhi? What were the formative moments of Dr Sodhi’s career? What are the new frontiers of cardiology?
Read More
EP 42: Dr Hafiza Khan on Trust, Patient Outreach and Instagram
EP42 • Feb 22, 2021 • 45m 37s
In one of her many posts on Instagram, we can see Dr Hafiza Khan holding a table summarising her reactogenicity after her second COVID shot. In the frame next to her is her son listing his own reactions. In this episode, Ankur asks Hafiza to talk about Instagram and reaching millennial and gen Z audiences, as well as the importance of developing and maintaining trust between different communities at a time of information overload.
Read More
EP 41: Mallory Abbott on Ebstein’s Anomaly, Self-Care & Gratitude
EP41 • Feb 09, 2021 • 42m 26s
Mallory was not prepared when she underwent her first heart surgery in seventh grade: She was hoping to regain her stamina, instead she experienced what she describes as a loss of self. Mallory was born with a rare heart disease called a Ebstein’s anomaly.
Read More
40: Mentorship, Reflection & the Journey of Mandeep R Mehra
EP40 • Jan 25, 2021 • 46m 33s
How does Dr Mehra think about building opportunities? What were his formative experiences? How does he think about the role of mentorship in medicine? What is Dr Mehra’s message to our listeners?Dr Mehra does not frame his experiences as failures or successes; he looks at all events with one question in mind: What can I learn from this?

In this week’s episode Ankur’s guest is Dr Mandeep R Mehra, Medical Director of Brigham Heart and Vascular Center and Professor of Medicine at Harvard Medical School.
Read More
EP 39: The Year 2020 in Review with Sukh Nijjer
EP39 • Jan 21, 2021 • 1h 2m 19s
In the first Parallax episode of 2021, Ankur welcomed back Sukh Nijjer from Imperial College London to review the most impactful events and advances in cardiology from 2020.

Which COVID19 patients require risk stratification with a stress test? What are the take-home messages for physicians taking care of patients diagnosed with COVID19? What were the key trials of 2020? What can we learn from the negative results of the STRENGHT study? How have studies like STOP-AF influenced clinical practice?
Read More
03: Athena Poppas On Effective Management Of Hypertension
EP03 • Apr 23, 2020 • 29m 43s
This week’s podcast guest needs no introduction! Prof Athena Poppas is one of the most widely known cardiologists in the US and current Vice-President of the American College of Cardiology! Ankur spoke to Athena about her recently published US Cardiology Review 13.1 article on whether early management of hypertension by GPs can improve outcomes.



They discuss the importance of preventative medicine, their experience of reducing hypertension with non-pharmaceutical and pharmaceutical methods, and the significance of the integrated “team approach” when treating comorbid conditions such as hypertension. Athena also shares her thoughts on cardiologists’ responsibility to shape their patients’ lifestyle choices.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
High-Sensitivity Cardiac Troponin ACS
EP02 • Apr 23, 2020 • 29m 55s
Ankur is back with his second #AudioArticle! This week he spoke with Santiago Garcia from the Minneapolis Heart Institute about Santiago’s US Cardiology Review 13.1 article on the role of high-sensitivity cardiac troponin (hscTn) assays and their ability to rapidly rule in or rule out acute coronary syndrome (ACS) with improved sensitivity.



Chest pain is one of the most common reasons for an emergency room visit in the US, with almost 6 million ER visits annually, yet there is no consensus on how to compare the results from various hscTn assays. Tune in to hear Santiago outline the advantages and limitations of using hscTn as a standard biomarket to evaluate patients with suspected ACS in the ER.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
01: Conduction Abnormalities After TAVR/TAVI With Chad Kliger
EP01 • Apr 23, 2020 • 27m 44s
In our first episode, Ankur explains his vision for and inspiration to start ‘Parallax’, and speaks with Chad Kliger from Lenox Hill Hospital in New York about conduction abnormalities after transcatheter aortic valve replacement (TAVR/TAVI), a review article published in US Cardiology Review 13.1 Ankur and Chad look at conduction abnormalities after TAVR/TAVI with a focus on basic conduction system anatomy in relation to the aortic valve, the mechanism, incidence, predisposing factors for occurrence, impact on mortality and finally, proposed treatment algorithms for management. Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More