Parallax AHA Edition: 3 Trials that will change your practice with Dr Amit Khera
Parallax AHA Edition: 3 Trials that will change your practice with Dr Amit Khera

Average (ratings)
No ratings
 
  Your rating

In this AHA 2021 episode of Parallax, Dr Ankur Kalra’s guest is Dr Amit Khera, Professor and Director of Preventive Cardiology at UT Southwestern Medical Center, Dallas and Vice Chair of the Scientific Sessions.

For this week’s show, Dr Khera selected three thought-provoking late-breaking trials that will inform or change clinical practice. Ankur and Amit discuss how the AVATAR trial will influence guidelines, and whether these findings could be translated to TAVR. Most importantly, they discuss how AVATAR’s results could inform patient decisions.
Next, Dr Khera highlights a randomized trial that was designed to address the needs of a larger population. The China Rural Hypertension Control Project offers exciting insights and an innovative framework for relying on social healthcare work.
Lastly, Dr Kalra and Dr Khera discuss a trial that investigated the LDL-cholesterol lowering efficacy of MK-0616. This oral PCSK9 Inhibitor may open the door for more patients in the future.

 

What were the key findings? What are the take-home messages? How will these 3 trials foster new opportunities for patients?

Trials covered in detail include:
• Aortic Valve Replacement versus Watchful Waiting in Asymptomatic Severe Aortic Stenosis: The Avatar Trial
• A Cluster Randomized Trial of a Village Doctor-Led Intervention on Blood Pressure Control: China Rural Hypertension Control Project
• The Clinical Safety, Pharmacokinetics, and LDL-Cholesterol Lowering Efficacy of MK-0616, an Oral PCSK9 Inhibitor

 

Questions and comments can be sent to “podcast@radcliffe-group.com” and may be answered by Ankur in the next episode. Guest @dramitkhera hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Brought to you by Edwards: www.edwardstavr.com

 


Read MoreRead Less
Share
Brought to you by Edwards: www.edwardstavr.com

Brought to you by Edwards: www.edwardstavr.com

Read MoreRead Less
Up Next
EP 60: The Year 2021 in Review with Dr Sukh Nijjer – Part 1| recent cardiology trials
EP60 • Dec 27, 2021 • 59m 18s
In the last Parallax episode of the year, Dr Ankur Kalra welcomed back Dr Sukh Nijjer, Interventional Cardiologist from Imperial College London, to review the most impactful events and advances in cardiology from 2021.
Read More
All Episodes
03: Athena Poppas On Effective Management Of Hypertension
EP03 • Apr 23, 2020 • 29m 43s
This week’s podcast guest needs no introduction! Prof Athena Poppas is one of the most widely known cardiologists in the US and current Vice-President of the American College of Cardiology! Ankur spoke to Athena about her recently published US Cardiology Review 13.1 article on whether early management of hypertension by GPs can improve outcomes.



They discuss the importance of preventative medicine, their experience of reducing hypertension with non-pharmaceutical and pharmaceutical methods, and the significance of the integrated “team approach” when treating comorbid conditions such as hypertension. Athena also shares her thoughts on cardiologists’ responsibility to shape their patients’ lifestyle choices.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
High-Sensitivity Cardiac Troponin ACS
EP02 • Apr 23, 2020 • 29m 55s
Ankur is back with his second #AudioArticle! This week he spoke with Santiago Garcia from the Minneapolis Heart Institute about Santiago’s US Cardiology Review 13.1 article on the role of high-sensitivity cardiac troponin (hscTn) assays and their ability to rapidly rule in or rule out acute coronary syndrome (ACS) with improved sensitivity.



Chest pain is one of the most common reasons for an emergency room visit in the US, with almost 6 million ER visits annually, yet there is no consensus on how to compare the results from various hscTn assays. Tune in to hear Santiago outline the advantages and limitations of using hscTn as a standard biomarket to evaluate patients with suspected ACS in the ER.



Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
01: Conduction Abnormalities After TAVR/TAVI With Chad Kliger
EP01 • Apr 23, 2020 • 27m 44s
In our first episode, Ankur explains his vision for and inspiration to start ‘Parallax’, and speaks with Chad Kliger from Lenox Hill Hospital in New York about conduction abnormalities after transcatheter aortic valve replacement (TAVR/TAVI), a review article published in US Cardiology Review 13.1 Ankur and Chad look at conduction abnormalities after TAVR/TAVI with a focus on basic conduction system anatomy in relation to the aortic valve, the mechanism, incidence, predisposing factors for occurrence, impact on mortality and finally, proposed treatment algorithms for management. Hosted by @AnkurKalraMD. Produced by @RadcliffeCardiology.
Read More
EP 48: Supporting India During COVID: Prof Madhav Swaminathan, Duke Health and ASE Humanitarian Aid
EP48 • May 17, 2021 • 40m 3s
"A failure to finish is a failure to start"

In this week's latest podcast episode, host, Ankur Kalra, MD, meets guest Prof Madhav Swaminathan (Duke University Health System, NC, US) to discuss how he has orchestrated a major humanitarian effort, in association with Duke University Health and The American Society of Echocardiography, to supply ventilation equipment and PPE to hospitals and NGOs during the current COVID-19 crisis in New Delhi, India.

Hear them discuss the challenges and learnings associated with the supply chain, inventory, logistics and cost to deliver this humanitarian effort; which most recently resulted in $140,000 of life-changing equipment being delivered to four key hospitals in New Delhi. A most inspirational episode.
Read More
EP 47 CardioNerds Meets Parallax: An Examined Life with Dr Ankur Kalra, Cardiologist, Writer & Podcaster
EP47 • May 03, 2021 • 1h 8m 3s
Over the past two years, Parallax listeners have gotten to know Dr Ankur Kalra through his conversations with our guests. In this episode, we turned the tables and invited CardioNerds co-founder Dr Amit Goyal to reintroduce Dr Ankur Kalra interventional cardiologist, researcher, writer, and the host of this podcast.
In this candid and spiritual conversation Amit and Ankur take a journey through former episodes of Parallax and Ankur’s writings to explore what it takes to strive for a deeper knowledge of ourselves; or, as Ankur puts it, dharma, the inherent order of reality.
Read More
EP 46 Dr Eric Adler on Mission, Mentorship & Synergy Between Research & Patient Care
EP46 • Apr 19, 2021 • 1h 6s
According to Dr Eric Adler, at the core of all impactful research is a powerful narrative that makes us reflect on the human condition. In 2006, when the ground-breaking discovery was made that specialized cells can be turned into stem cells, Dr Eric Adler was thinking about how he could create a synergy between his passion for clinical work and his determination to ask compelling questions in research.

Parallax’s guest this week is Dr Eric David Adler, Medical director of heart transplant and mechanical circulatory support at UC San Diego Health.
Read More
EP 45: The Journey of Dr Alin Gragossian, Physician, Heart Transplant Recipient & Advocate
EP45 • Apr 05, 2021 • 36m 46s
Dr Ankur Kalra’s guest is Dr Alin Gragossian, a critical care fellow, heart transplant recipient and advocate. In this episode, Alin talks about her journey as a patient, the psychological aspects of her recovery and her advocacy work. Ankur asks Alin about the mindset behind her sense of purpose and her dedication to help raise awareness of organ donation and young heart failure patients.

How did Dr Gragossian receive her diagnosis? How does she feel about her new reality? What drives her? What is her message to our listeners?
Read More
EP 44: Refugee, Dishwasher, Cardiologist, Humanitarian: The Journey of Dr H
EP44 • Mar 22, 2021 • 46m 8s
How can we use our power and privilege to serve? How did his experiences shape Dr Kelli to become an ambassador for his community? What is his message to our listeners?
Just after 9/11, Heval, the 18-year-old Syrian Kurdish refugee found a job as a dishwasher. At this point, he was the sole provider of his family. The pressure that comes from being poor did not leave him for many years. Today, he is firm believer in giving back to underserved communities by spreading awareness within the medical community. As he says, well-meaning people of privilege are sometimes afraid to act. What we need is more people to bridge the gap and find ways to help each other.
Read More