Parallax AHA Edition: 3 Trials that will change your practice with Dr Amit Khera
Parallax AHA Edition: 3 Trials that will change your practice with Dr Amit Khera

Average (ratings)
No ratings
 
  Your rating

In this AHA 2021 episode of Parallax, Dr Ankur Kalra’s guest is Dr Amit Khera, Professor and Director of Preventive Cardiology at UT Southwestern Medical Center, Dallas and Vice Chair of the Scientific Sessions.

For this week’s show, Dr Khera selected three thought-provoking late-breaking trials that will inform or change clinical practice. Ankur and Amit discuss how the AVATAR trial will influence guidelines, and whether these findings could be translated to TAVR. Most importantly, they discuss how AVATAR’s results could inform patient decisions.
Next, Dr Khera highlights a randomized trial that was designed to address the needs of a larger population. The China Rural Hypertension Control Project offers exciting insights and an innovative framework for relying on social healthcare work.
Lastly, Dr Kalra and Dr Khera discuss a trial that investigated the LDL-cholesterol lowering efficacy of MK-0616. This oral PCSK9 Inhibitor may open the door for more patients in the future.

 

What were the key findings? What are the take-home messages? How will these 3 trials foster new opportunities for patients?

Trials covered in detail include:
• Aortic Valve Replacement versus Watchful Waiting in Asymptomatic Severe Aortic Stenosis: The Avatar Trial
• A Cluster Randomized Trial of a Village Doctor-Led Intervention on Blood Pressure Control: China Rural Hypertension Control Project
• The Clinical Safety, Pharmacokinetics, and LDL-Cholesterol Lowering Efficacy of MK-0616, an Oral PCSK9 Inhibitor

 

Questions and comments can be sent to “podcast@radcliffe-group.com” and may be answered by Ankur in the next episode. Guest @dramitkhera hosted by @AnkurKalraMD. Produced by @RadcliffeCARDIO.
Brought to you by Edwards: www.edwardstavr.com

 


Read MoreRead Less
Share
Brought to you by Edwards: www.edwardstavr.com

Brought to you by Edwards: www.edwardstavr.com

Read MoreRead Less
Up Next
EP 60: The Year 2021 in Review with Dr Sukh Nijjer – Part 1| recent cardiology trials
EP60 • Dec 27, 2021 • 59m 18s
In the last Parallax episode of the year, Dr Ankur Kalra welcomed back Dr Sukh Nijjer, Interventional Cardiologist from Imperial College London, to review the most impactful events and advances in cardiology from 2021.
Read More
All Episodes
EP 73: Passion, Faith & Entrepreneurship with Prof Carolyn Lam, Clinician Scientist
EP73 • Jul 04, 2022 • 47m 56s
In this refreshing and spiritual episode Carolyn reflects on her journey and the decisions and mentors that shaped her career as a heart failure specialist, trialist and as a public speaker. Ankur and Carolyn dive into the question whether being balanced is what we should be all aiming for. Ankur asks Carolyn about her work as a co-founder of Us2.ai, a start-up dedicated to the automation of the fight against heart disease by applying AI to echocardiography.
Read More
Burnout, Clinician Wellbeing & Reforming Medicine with Dr Fisher
EP72 • Jun 20, 2022 • 45m 51s
This week’s guest on Parallax is Dr Jonathan Fisher Cardiologist and Organizational Well-Being and Resiliency Leader at Novant Health.
Read More
EP 71: Cardiology News, Journalism & Leadership with Shelley Wood
EP71 • Jun 06, 2022 • 49m 15s
In this engaging episode, Ankur asks Shelley about her journey to medical journalism from theheart.org to TCTMD. Shelley recalls the early days of online news and shares her thoughts on what makes a content stand out in 2022. We learn more about the editorial decisions that go into leading one of the most trusted cardiology news services. Shelley, author of a bestselling novel, talks about how she balances her journalistic work with her creative writing.
Read More
EP 70: Technological Ecosystem, Innovation & Personalised Medicine with Dr Ami Bhatt
EP70 • May 23, 2022 • 45m 59s
In this engaging and in-depth episode, Dr Kalra and Dr Bhatt talk about the state of digital transformation today: They discuss the challenges and opportunities of telemedicine, artificial ‘collaborative’ intelligence and novel technologies that could enhance medical training. Dr Kalra asks Dr Bhatt about how she balances her responsibilities and her tips for approaching complex problems. Dr Bhatt also shares insights on the practicalities of her role as Chief Innovation Officer of ACC.
Read More
EP 69: Global Health, AI and Telemedicine with Dr Hunter Cherwek
EP69 • May 09, 2022 • 42m 4s
In this unique episode Dr Kalra and Dr Cherwek discuss highly innovative solutions in ophthalmology that could be implemented in cardiovascular medicine.
They talk about AI assisted consultation, learning pathways incorporating simulators for early career practitioners and the Flying Eye Hospital. Dr Cherwek shares his experiences about working with local teams globally and the work that goes into setting up trials across the world.
Read More
EP 68: Public Health, Fighting Misinformation and TikTok with Dr Muhammad Siyab
EP68 • Apr 25, 2022 • 46m 31s
In a 1-minute video, wearing scrubs, Dr Siyab, Md voices his concerns over the decision to end mask mandate on certain US airlines. “The people that are so intensely against these mask mandates, they are not the ones who are taking buses or trains to get to work and get back home every day because they are part of the privileged class.” Dr Siyab’s mission is to be a voice of reason and appeal to those who are hesitant or against getting vaccines. His plight goes out to his 405.3K followers on TikTok every day.
Read More
EP 67: Guidelines, Inequality and Moving the Needle with Dr Devesh Rai and Dr Martha Gulati
EP67 • Apr 11, 2022 • 46m 9s
Why are we talking about inclusion, diversity, and equity? Recent years have seen many studies on the inequalities in representation of women in cardiology and yet the needle has not been moved as much as we hoped for. What does the data on the authorship of the guidelines tell us and what can be done to balance the scale?
Dr Ankur Kalra’s guests this week are Dr Martha Gulati, internationally recognized cardiologist specializing in Women and Heart Disease, Heart Disease Prevention and Dr Devesh Rai, first year cardiology fellow at Rochester General Hospital.
Read More
EP 66: Goal Setting, Tenure Track & Positive Mindset with Dr Nadia Sutton
EP66 • Mar 28, 2022 • 49m 53s
In this engaging and constructive episode, Nadia recalls her journey to medicine and reflects on the life decisions she had to make along the way: What is the career path that will get us closer to our mission? When is the right time to start family planning? How can we develop resilience in face of rejection? Nadia recalls the conversations with her colleagues and mentors as she progressed in her career. She talks about the practical aspects of tenure track and grant application. Ankur and Nadia discuss the importance of goal setting and exercising a positive mindset.
Read More
EP 65: Industry Pathway ,“Who” Luck, and Thinking Big with Dr Shon Chakrabarti
EP65 • Mar 14, 2022 • 41m 44s
In this rich and candid episode, Dr Chakrabarti recalls the early stages of his career and the non-linear route that led to his transition from an interventional cardiologist to working on devices that focus on improving the treatment of deep vein thrombosis (DVT). This journey was paved by self-reflection, hunger for tangible results, and connections with mentors who dared to dream big and wished the same for their mentees.
Read More
EP 64: Patient Advocate, CHD Care and the Mission of Team Uncle Joe with Joe Valente
EP64 • Feb 28, 2022 • 30m 41s
Parallax host Dr Ankur Kalra invites Joe Valente, a Board-Certified Patient Advocate (BCPA) and Co-Founder of Team Uncle Joe, to talk about his mission and practical considerations involving CHD care both from a patient and a healthcare provider perspective. In this informative and practical episode, Joe shares details about the process of getting certified as a BCPA and about the work that goes into setting up a non-profit organization. We learn more about how he and his team can support patients with CHD and what he considers to be the pillar of good patient-doctor communication.
Read More
EP 103: CCS-AMI: New Classification for Acute Myocardial Infarction with Dr Kumar
EP103 • Oct 30, 2023 • 42m 43s
In this informative episode, Dr Kumar shares what led his team and the CCS to introduce a new classification scheme for acute MI. He discusses how research from the past 15 years highlighted the need to incorporate tissue changes resulting from acute myocardial infarction (MI) into clinical practice. Dr Kumar outlines the four stages of CCS-AMI, and we gain insight into how this novel classification scheme could impact bedside medicine.
Read More
EP 102: Nobility in Small Things with Cardiac Surgeon, Dr Craig R Smith
EP102 • Oct 16, 2023 • 50m 11s
In this inspiring episode, Dr Smith delves into the story behind his book and the motivating circumstances that led him to become an author. Dr Kalra asks Dr Smith about his experience as a leader during the pandemic as a surgeon. Dr Smith shares the story of his unconventional journey into medicine, emphasizing how hard physical labor built his resilience and prepared him for his residency. Dr Kalra also asks about Dr Smith's experience as a surgeon for President Bill Clinton in 2004.
Read More
EP 101: Translating Evidence, Innovations & Value for Patients with Dr John Mandrola
EP101 • Sep 25, 2023 • 47m 13s
In this insightful episode, we delve into Dr. Mandrola's career journey. He discusses how the beginnings of his career during a period of significant innovations and the reversal of expert opinions profoundly influenced his perspective on medicine, leading to a more conservative stance. Dr. Kalra then invites Dr. Mandrola to share the motivations that drive his work as a medical journalist and communicator, along with his methods of selecting studies to highlight in his writings and show.
Read More
EP 100: Conversation with Dr Valentin Fuster: Trust, Fulfilment & Leadership
EP100 • Sep 15, 2023 • 54m 38s
In this candid and rich episode, Dr Fuster invites us to contemplate the concepts of mentorship and trust by recounting pivotal moments from his life, revealing how these principles propelled him towards a life of fulfilment.
Read More
EP 99: ESC 23 Review: Interventional Trials with Dr Mirvat Alasnag
EP99 • Sep 04, 2023 • 36m 34s
Dr. Alasnag and Dr. Kalra provide a comprehensive review of the key highlights from ESC Congress 2023. Dr. Alasnag distills the background and latest evidence from key interventional trials, emphasizing their significance for patient care.
Tune in to discover the strategies that Dr. Kalra and Dr. Alasnag are currently employing and gain insights into how these data will shape their future decision-making in the catheterization laboratory. Don't miss this informative discussion at the forefront of interventional cardiology.
Read More