In This Section:
Pulmonary Embolism
Venous thromboembolism is a serious disease. Both deep vein thrombosis and pulmonary embolism frequently result in devastating impacts for patients in both the short and the long term. Pulmonary Embolism affects about 1000 out of every 1 million people with 200 of those cases considered to have an intermediate-high and high risk of mortality. Pulmonary Embolism, while preventable, is the 3rd leading cause of cardiovascular death.
As high mortality rates have shown little improvement over the last 20 years, it is clear acute PE patients need to be managed differently. We know that conservative treatment options, as recommended by the guidelines leave thrombus behind in 20-50% of the patients. Literature shows the mortality number on anticoagulation only is still high and the majority of venous clot is lytic-resistant by time of treatment. Thrombolysis comes with significant risk of bleeds.
This section presents key papers, IHR and HR PE case reports and also interviews with the Key Opinion Leaders discussing on how new technologies, like a lytic-free thrombectomy, can transform the treatment of acute Pulmonary Embolism.
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Section Advisor
Prof Felix Mahfoud
The Pulmonary Embolism section is supported by
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Recent Videos
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Case Studies
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Poor H, Serrao G, Grapsa J, et al. J Am Coll Cardiol. 2023;81:283–91.
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Clinical publications
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Ramakrishnan G, Willie-Permor D, Yei K, et al. J Vasc Surg Venous Lymphat Disord. 2023;11:587–94.e3.
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Ismail U, Rowe RA, Cashin J, et al. Sci Rep. 2022;12:5295.
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Agarwal MA, Dhaliwal JS, Yang EH, et al. Chest. 2023;163:216–25.
Piliero N, Guichard A, Bedague D, et al. JACC Cardiovasc Interv. 2022;15:1994–5.
Bashir R, Foster M, Iskander A, et al. JACC Cardiovasc Interv. 2022;15:2427–36.
Ito R, Yamashita J, Nakajima Y, et al. JACC Cardiovasc Interv. 2023;16:986–7.
Andersen A, Musialek P, Araszkiewicz A, et al. JACC Cardiovasc Interv. 2023;16:623–25.
Bangalore S, Horowitz JM, Beam D, et al. JACC Cardiovasc Interv. 2023;16:958–72.
Wiedenroth CB, Rolf A, Steinhaus K, et al. J Heart Lung Transplant. 2023;42:134–9.
Bikdeli B, Caraballo C, Trujillo-Santos J, et al. JAMA Cardiol. 2022;7:857–65.
Sadeghipour P, Jenab Y, Moosavi J, et al. JAMA Cardiol. 2022;7:1189–97.
Jiménez D, Rodríguez C, León F, et al. Eur Respir J. 2022;59:2100412.
de Jong CMM, Visser C, Bemelmans RHH, et al. Eur Respir J. 2023;61:2300171.
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Thienel M, Müller-Reif JB, Zhang Z, et al. Science. 2023;380:178–87.
Jabagi MJ, Bertrand M, Botton J, et al. N Engl J Med. 2023;388:1431–2.
Guidelines
Bangalore S, Horowitz JM, Beam D, et al. JACC Cardiovasc Interv 2023;16:958-72.
Porcaro K, Haines J, Morris S, et al. J Am Coll Cardiol 2019;73:2046.
Khandhar SJ, Mehta M, Cilia L, et al. Catheter Cardiovasc Interv 2020;95:13-18.
Vanni S, Jiménez D, Nazerian P, et al. Thorax 20215;70:333-8.
Ebner M, Pagel CF, Sentler C, et al. 2021;86:25-21.
Jaureguízar A, Jiménez D, Bikdeli B, et al. Chest 2022;161:524-34
Jimenez D, Aujesky D, Díaz G, et al. AM J Respir Crit Care Med 2010;181:983-91.
Meinel F, Nance J, Schoepf U, et al. Am J Med 2015;128:747–59.
Sánchez F, Martinez J, Echezarrata M, et al. N AM J Med Sci 2016;8:134–42.
Guidelines and Consensus
Konstantinides SV, Meyer G, Becattini C, et al. Eur Heart J. 2020;41:543–603.
Pruszczyk P, Klok FA, Kucher N, et al. EuroIntervention. 2022;18:e623–38.
Kanjee Z, Freed JA, Carroll BJ, et al. Ann Intern Med. 2022; 175:1161–69.
Goldberg JB, Giri J, Kobayashi T, et al. Circulation. 2023;147:e628–47.
Humbert M, Kovacs G, Hoeper MM, et al. Eur Heart J. 2022;43:3618–731.
Review Articles
Cueto-Robledo G, Rivera-Sotelo N, Roldan-Valadez E, et al. Curr Probl Cardiol. 2022;47:101294.
Kochar A, Bergmark BA. Eur Heart J Acute Cardiovasc Care. 2022;11:721–7.
Inman BL, Long B. Ann Emerg Med. 2023;81:580–3.
Ross C, Kumar R, Pelland-Marcotte MC, et al. Chest. 2022;161:791–802.
Harvey JJ, Huang S, Uberoi R. Cochrane Database Syst Rev. 2022;8:CD013083.
Warren RE, Dhruva SS, Kinard M, et al. JAMA Intern Med. 2023;183:271–2.
Rezende SM. Lancet Haematol. 2023;10:e11.
Freund Y, Cohen-Aubart F, Bloom B. et al. JAMA. 2022;328:1336–45.
Walter K. JAMA. 2023;329(1):104.
Systematic Analysis
Ismayl M, Machanahalli Balakrishna A, et al. Am J Cardiol. 2022;178:154–62.
Alshaqaq HM, Al-Sharydah AM, Alshahrani MS, et al. J Intensive Care Med. 2023;38:491–510.
Mathew D, Kim J, Kosuru BP, et al. Sci Rep. 2023;13:7169.
Fernando SM, Tran A, Cheng W, et al. Chest. 2022;161:418–28.
Jain N, Sheikh MA, Bajaj D, et al. JACC Cardiovasc Interv. 2023;16:976–83.
Le Roux PY, Schafer WM, Blanc-Beguin F, et al. Clin Nucl Med. 2023;48:8–17.
Chopard R, Nielsen P, Ius F, Cebotari S, et al. Eur Respir J. 2022;60:2102977.